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Publié le 09/04/2014
Intensive industrial data collection using sample changer by VERNALIS, on PROXIMA 1: 110...
Vernalis is a pharmaceutical company with a strong focus on Structure Based Drug Design (SBDD). Protein Crystallography plays an important role in our research.
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Publié le 06/02/2014
Near-infrared for improved detection of luminescent nano-compounds in living cells
Fluorescence imaging is an emerging technique for biomedical applications. It can be used to observe and track a specific target (constituents of the cell, pathogen, active ingredient, etc.) in real...
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Publié le 21/01/2014
X-ray Phase Imaging
X-ray radiography based on absorption contrast is one of the efficient techniques allowing probing matter in depth. However, its analysis capabilities are strongly limited, when the elementary parts...
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Publié le 06/12/2013
Tracking the accumulation of antibiotic molecules in resistant bacteria
The Joint Research Unit UMR-MD1, Aix-Marseille University, has been working with the DISCO beamline for several years to develop a non-invasive, non-perturbing method of determining the concentration...
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Publié le 27/11/2013
Which protein is responsible for uranium accumulation in the skeleton?
Radiochemists from CNRS/Université Paris-Sud Orsay (IPNO) and CNRS/ Université de Nice-Sophia Antipolis (ICN) and biologists from the life science CEA division (DSV) collaborated with the MARS...
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Publié le 11/10/2013
Of mice and men… and uric acid
In humans an excess of uric acid (or hyperuricemia) is associated with, or responsible for several serious health problems: metabolic syndrome
1
, gout and kidney dysfunction. Other living...
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Publié le 09/07/2013
Transmission of nerve impulses – New data about the 3D structure of ion channels toward a...
The pentameric ligand-gated ion channels (pLGICs) constitute a large family of ionotropic receptors that are ubiquitously represented in the animal kingdom. In vertebrates, the family encompasses...
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Publié le 07/06/2013
Transmission of nerve impulses - New structural data helps to understand the action of...
Benzodiazepines are among the most commonly prescribed psychotropic drugs in the world, used to treat anxiety, insomnia, convulsions, spasms, etc. These molecules act by binding to specific sites at...
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Publié le 06/06/2013
First structure of a rubella virus envelope protein
In the context of research on viral fusion proteins, researchers from the Structural Virology Unit at the Pasteur Institute, led by Felix Rey, have determined the first structure of a rubella virus...
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