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Publié le 08.23.2024

How coronavirus HKU1 forces its way into cells

Scientists from the Pasteur Institute have pinpointed the precise binding sites for the coronavirus HKU1 in respiratory cells, providing a detailed picture of the infection mechanism used by the virus. Their findings shed light on other animal species that may host the virus and pave the way for the development of infection-blocking antibodies. SOLEIL's PROXIMA-1 and PROXIMA-2A beamlines...

Publié le 11/04/2024

A 300 keV cryo-electron microscope available at SOLEIL by 2025

On Monday 18 March 2024, over 8 tons of equipment have been delivered to SOLEIL. These are parts for the new cryogenic electron microscope, which will be made available to users, on the basis of a...

Publié le 27/09/2023

Combining computer design and structural biology to develop future leukemia drugs

Acute T-cell lymphoblastic leukemia is notorious for its high relapse rate and resistance to standard treatments, considerably limiting patients' chances of long-term survival. A team of researchers...

Publié le 05/07/2023

SOLEIL Highlights 2022

This document presents a selection of the remarkable results achieved by our users and teams. They allow us to remain optimistic for the future, despite a difficult context linked to the...

Publié le 12/04/2023

SOLEIL’s contribution to understanding viruses

After 15 years of opening to our users, SOLEIL takes stock of the important results obtained thanks to the beamlines during this period. Thus, we invite you to discover a series of thematic brochures...

Publié le 15/03/2023

Molecular mechanism of LDL cholesterol regulation

In a crucial step towards understanding the mechanisms of cardiovascular disease and certain cancers, a research team has achieved a world first: finding the molecular mechanism by which the PCSK9...

Publié le 22/02/2023

SOLEIL Health & Well-Being scientific section meets biologists from the plateau de...

On February 1st, 2023, the Health & Well-Being scientific section of SOLEIL organised a day of presentations and discussions for biologists from the plateau de Saclay area, at the Institute for...

Publié le 29/06/2022

SOLEIL Highlights 2021

The non-profit civil company Synchrotron SOLEIL was created in 2001. This new edition of our Highlights looks back on the twentieth anniversary of this creation, a year still marked by the pandemic...

Publié le 01/03/2022

Monitoring the motion of a microbiome enzyme involved in methane biosynthesis

The largest and most diverse family of enzymes are the so-called radical SAM enzymes. They catalyse a large number of major biochemical reactions often unprecedented in living cells, notably for the...

Publié le 24/01/2022

Light activates a molecular virulence switch in the bacterium responsible for the “black...

Researchers from the Fundación Instituto Leloir in Argentina together with scientists from PROXIMA-1 & PROXIMA-2A beamlines were able to describe at a molecular level the conformational changes...

Publié le 05/08/2021

How deep-sea microbes make a life on ethane? Answers in a yellow crystal

Various hydrocarbons are naturally released in the deep-sea floor, but something in the marine sediments consumes them. The responsible are specific microorganisms, able to transform these...

Publié le 27/07/2021

SOLEIL Highlights 2020

It is obviously impossible to summarize the year 2020 without mentioning the COVID-19 pandemic, which forced us all to change our way of interacting and working. However, the...