Last update : 08.23.2025
Ammar Khodja, L., Campanacci, V., Lippens, G., Gigant, B. "The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization" PNAS Nexus., 3(11): art.n° 487. (2024).
Antonini, G., Bernardi, A., Gillon, E., Dal Corso, A., Civera, M., Belvisi, L., Varrot, A., Mazzotta, S. "Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands" Journal of Medicinal Chemistry., 67(21): 19546-19560. (2024).
Kyriazi, D., Voth, L., Bader, A., Ewert, W., Gerlach, J., Elfrink, K., Franz, P., Tsap, M.I., Schirmer, B., Damiano-Guercio, J., Hartmann, F.K., Plenge, M., Salari, A., Schöttelndreier, D., Strienke, K., Bresch, N., Salinas, C., Gutzeit, H.O., Schaumann, N., Hussein, K., Bähre, H., Brüsch, I., Claus, P., Neumann, D., Taft, M.H., Shcherbata, H.R., Ngezahayo, A., Bähler, M., Amiri, M., Knölker, H.J., Preller, M., Tsiavaliaris, G. "An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells" Nature Communications., 15: art.n° 9947. (2024).
Megalizzi, V., Tanina, A., Grosse, C., Mirgaux, M., Legrand, P., Dias Mirandela, G., Wohlkönig, A., Bifani, P., Wintjens, R. "Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family" Heliyon., 10(22): art.n° e40494. (2024).
Vantieghem, T., Aslam, N.A., Osipov, E.M., Akele, M., Van Belle, S., Beelen, S., Drexler, M., Paulovcakova, T., Lux, V., Fearon, D., Douangamath, A., von Delft, F., Christ, F., Veverka, V., Verwilst, P., Van Aerschot, A., Debyser, Z., Strelkov, S.V. "Rational fragment-based design of compounds targeting the PWWP domain of the HRP family" European Journal of Medicinal Chemistry., 280: art.n° 116960. (2024).
Collin, S., Weissman, K.J., Gruez, A. "Structural Plasticity within 3-Hydroxy-3-Methylglutaryl Synthases Catalyzing the First Step of β-Branching in Polyketide Biosynthesis Underpins a Dynamic Mechanism of Substrate Accommodation" JACS Au., 4(10): 3833–3847. (2024).
da Silva Lameira, C., Münßinger, S., Yang, L., Eikmanns, B.J., Bellinzoni, M. "Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features" FEBS Journal., 290(20): 4501-4521. (2024).
Wallace, M.D., Cuxart, I., Roret, T., Guée, L., Debowski, A.W., Czjzek, M., Rovira, C., Stubbs, K.A., Ficko-Blean, E. "Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation" Angewandte Chemie International Edition., 63(43): art.n° e202411171. (2024).
Ray, J., Clegg, B., Grembecka, J., Cierpicki, T. "Drug-resistant menin variants retain high binding affinity and interactions with MLL1" Journal of Biological Chemistry., 300(10): art.n° 107777. (2024).
Barbarin-Bocahu, I., Ulryck, N., Rigobert, A., Ruiz Gutierrez, N., Decourty, L., Raji, M., Garkhal, B., Le Hir, H., Saveanu, C., Graille, M. "Structure of the Nmd4-Upf1 complex supports conservation of the nonsense-mediated mRNA decay pathway between yeast and humans" PLoS Biology., 22(9): art.n° e3002821. (2024).