Last update : 06.07.2025
Legru, A., Batista, F.A., Puszko, A.K., Bouillon, A., Maurel, M., Martinez, M., Ejjoummany, A., Ortega Varga, L., Adler, P., Méchaly, A., Hadjadj, M., Sosnowski, P., Hopfgartner, G., Alzari, P.M., Blondel, A., Haouz, A., Barale, J.C., Hernandez, J.F. "Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1" European Journal of Medicinal Chemistry., 269: art.n° 116308. (2024).
Martinez, M., Bouillon, A., Brûlé, S., Raynal, B., Haouz, A., Alzari, P.M., Barale, J.C. "Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress" mBio., 15(3): art.n° 00198-24. (2024).
Asano, W., Hantani, R., Uhara, T., Debaene, F., Nomura, A., Yamaguchi, K., Adachi, T., Otake, K., Harada, K., Hantani, Y. "Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues" SLAS Discovery., 29(2): art.n° 100125. (2024).
Lundstrøm, J., Gillon, E., Chazalet, V., Kerekes, N., Di Maio, A., Feizi, T., Liu, Y., Varrot, A., Bojar, D. "Elucidating the glycan-binding specificity and structure of Cucumis melo agglutinin, a new R-type lectin" Beilstein Journal of Organic Chemistry., 20: 306–320. (2024).
Wallart, L., Ben Mlouka, M.A., Saffiedine, B., Coquet, L., Le, H., Hardouin, J., Jouenne, T., Phan, G., Kiefer-Meyer, M.C., Girard, E., Broutin, I., Cosette, P. "BacA: a possible regulator that contributes to the biofilm formation of Pseudomonas aeruginosa" Frontiers in Microbiology., 15: art.n° 1332448. (2024).
Kubiak, X., Polsinelli, I., Chavas, L.M.G., Fyfe, C.D., Guillot, A., Fradale, L., Brewee, C., Grimaldi, S., Gerbaud, G., Thureau, A., Legrand, P., Berteau, O., Benjdia, A. "Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme" Nature Chemical Biology., 20(3): 382–391. (2024).
Ouasti, F., Audin, M., Freon, K., Quivy, J.P., Tachekort, M., Cesard, E., Thureau, A., Ropars, V., Varela, P.F., Moal, G., Amadou, I.S., Uryga, A., Legrand, P., Andreani, J., Guerois, R., Almouzni, G., Lambert, S., Ochsenbein, F. "Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe" eLife., 12: art.n° RP91461. (2024).
Ľuptáková, E., Vigouroux, A., Končitíková, R., Kopečná, M., Zalabák, D., Novák, O., Salcedo-Sarmiento, S., Zeljković,S.C., Kopečný, D.J., von Schwartzenberg, K., Strnad, M., Spíchal, L., De Diego, N., Kopečný, D., Moréra, S. "Plant nucleoside N-ribohydrolases: riboside binding and role in nitrogen storage mobilization" Plant Journal., 117(5): 1432-1452. (2024).
Shannon, A., Chazot, A., Feracci, M., Falcou, C., Fattorini, V., Selisko, B., Good, S., Moussa, A., Sommadossi, J.P., Ferron, F., Alvarez, K., Canard, B. "An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex" Nucleic Acids Research., 52(3): 1325–1340. (2024).
Sake, S.M., Zhang, X., Rajak, M.K., Urbanek-Quaing, M., Carpentier, A., Gunesch, A.P., Grethe, C., Matthaei, A., Rückert, J., Galloux, M., Larcher, T., Le Goffic, R., Hontonnou, F., Chatterjee, A.K., Johnson, K., Morwood, K., Rox, K., Elgaher, W.A.M., Huang, J., Wetzke, M., Hansen, G., Fischer, N., Eléouët, J.F., Rameix-Welti, M.A., Hirsch, A.K.H., Herold, E., Empting, M., Lauber, C., Schulz, T.F., Krey, T., Haid, S., Pietschmann, T. "Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor" Nature Communications., 15: art.n° 1173. (2024).