PUBLICATIONS

Last update : 08/08/2026
  • El Ghachi, M., Howe, N., Huang, C.Y., Olieric, V., Warshamanage, R., Touzé, T., Weichert, D., Stansfeld, P.J., Wang, M., Kerff, F., Caffrey, M. "Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis" Nature Communications., 9: art. n° 1078. (2018).
  • Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018).
  • Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465-1481. (2017).
  • Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, D., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L. "Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate Reductoisomerase with β‐Arylpropyl Analogues of Fosmidomycin" ChemMedChem., 11(18): 2024-2036. (2016).
  • Bloch, Y., Bouchareychas, L., Merceron, R., Składanowska,K., Van den Bossche,L., Detry,S., Govindarajan,S., Elewaut,D., Haerynck,F., Dullaers,M., Adamopoulos,I.E., Savvides, S.N. "Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1" Immunity., 48(1): 45-58.e6. (2018).
  • Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, P., Charbonnier, J.B. "XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining" Nature Structural and Molecular Biology., 25(10): 971–980 . (2018).
  • Dorival, J., Risser, F., Jacob, C., Colin, S., Dräger, G., Paris, C., Chagot, B., Kirschning, A., Gruez, A., Weissman, K. J. "Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis" Nature Communications., 9: art.n° 3998. (2018).
  • Bandyra, K.J., Wandzik, J.M., Luisi, B.F. "Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E" Molecular Cell., 72(2): 275-285.e4. (2018).
  • Rinaldi, J., Fernández, I., Poth, L.M., Shepard, W.E., Savko, M., Goldbaum, F.A., Klinke, S. "Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state" Biochemistry and Biophysics Reports., 16: 39-43. (2018).
  • Kettle, J.G., Anjum, R., Barry, E., Bhavsar, D., Brown, C., Boyd, S., Campbell, A., Goldberg, K., Grondine, M., Guichard, S., Hardy, C.J., Hunt, T., Jones, R.D.O., Xiuwei Li, X., Moleva, O., Ogg, D., Overman, R.C., Packer, M.J., Pearson, S., Schimpl, M., Shao, W., Smith, A., Smith, J.M., Stead, D., Stokes, S., Tucker, M., Ye, Y. "Discovery of N‑(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)‑1H‑1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors" Journal of Medicinal Chemistry., 61(19): 8797–8810. (2018).