PUBLICATIONS

Last update : 08/08/2026
  • Mann, S.E., Lefranc, J., Alkhatib, O., Boivin, R., Bomke, J., Byrne, R.T., Cassona, C.P., Chen, X., Cornaciu, I., Costales, P., Davis, O.A., DeSelm, L., Elinati, E., Follows, B., Galbiati, A., Goldner, C., Hayre, J.K., Jorand-Lebrun, C., Lademann, C.A., Leuthner, B., Majithiya, J.B., Malta, C.F., Mason, B., McWhirter, C.L., Neff, B., Nissink, J.W.M., Pehl, U., Petersson, C., Pica, A., Pinto, M.F., Rajendra, E., Rakers, C., Toste Rego, A., Robinson, H.M.R., Sala-Hojman, A., Schaedler, T.A., Schurmann, P.J.L., Silva, D.O., Smith, G.C.M., Sorrell, F., Webster, G.R., Zenke, F.T., Heald, R.A., Burgdorf, L.T. "Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor" Journal of Medicinal Chemistry., 68(19): 20410–20434. (2025).
  • Nandwani, N., Bhowmik, D., Glaser, C., Childers, M.C., Goluguri, R.R., Dawood, A., Regnier, M., Houdusse, A., Spudich, J.A., Ruppel, K.M. "Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically" Nature Communications., 16: art.n° 8751. (2025).
  • Martinkus, J., Terradot, L., Jurėnas, D., Cascales, E. "Widespread deployment of the human CD38 ADP-ribosyl cyclase fold in antibacterial and anti-eukaryotic polymorphic toxins" Journal of Biological Chemistry., 301(11): art.n° 110775. (2025).
  • Ferchaud, N., Kopečný, D., Peřina,M., Boyer, A., Hentati, S., Pontoizeau, C., Desterke, C., Kryštof,V., Machover,D., Briozzo, P. "The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer" International Journal of Biological Macromolecules., 330(2): art.n° 147876. (2025).
  • Moussawi, M.A., Abdelhameed, S.A.M., de Azambuja, F., Wijten, A., Vasović, T., Ćirković Veličković, T., Parac-Vogt, T.N. "Fast and selective protein modification with ironsubstituted polyoxometalates via a radical pathway" Inorganic Chemistry Frontiers., 12(23): 7874-7882. (2025).
  • Vantieghem, T., Osipov, E.M., Beelen, S., Strelkov, S.V. "Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening" Acta Crystallographica F., 81(8): 358-364. (2025).
  • Kalandia, G., Declerck, K., Salazar Marcano, D.E., Gourmand, R., Moussawi, M.A., Parac-Vogt, T.N. "Finding the Key: Binding of Metal-Oxo Clusters to the Enzyme Active Site Enabled by “Click” (Bio)Conjugation" Angewandte Chemie International Edition., 64(50): art.n° e202518349. (2025).
  • Gerusz, V., Regenass, P., Rousseau, Q., Moraine, V., Justine Dao, J., Xavier Lavé, X., Das, S., Hue Perron, J., Fajas Descamps, L., Bravo, J., Dieppois, G., Kaplan, N., Lefebre, M., Altomari, D., Romanov, V., Finn, T., Daram, P., Bernardini, F., Gross, M., Lysek, R., Adam, A., Pohin, D., Maio, M., Tatsis, V., Sunose, M., Ronin, C., Ciesielski, F., Ahlstrand, J., Jacobsson, S., Unemo, M., Cameron, D.R "The bactericidal FabI inhibitor Debio 1453 clears antibiotic-resistant Neisseria gonorrhoeae infection in vivo" nature Communications., 16: art.n° 8309 . (2025).
  • Sarmadi, F., Caza, A., Gao, Z., Rochel, N., Gleason, J.L., White, J.H. "Hyperagonism of a Vitamin D Receptor Agonist/Histone Deacetylase Inhibitor Hybrid Molecule" Journal of Medicinal Chemistry., 68(19): 20675-20688. (2025).
  • Wehbi, H., Cece, Q., Phan, G., Broutin, I. "MexB/inhibitor complexes preparation for crystallography and cryo-EM, comparison and possible pitfalls" Methods in Enzymology., 724: 365-396. (2025).