PUBLICATIONS

Last update : 10/10/2026
  • Plé, C., Tam, H.K., Vieira Da Cruz, A., Compagne, N., Jiménez-Castellanos, J.C., Müller, R.T., Pradel, E., Foong, W.E., Malloci, G., Ballée, A. , Kirchner, M.A., Moshfegh, P., Herledan, A., Herrmann, A., Deprez, B., Willand, N., Vargiu, A.V., Pos, K.M., Flipo, M. , Hartkoorn, R.C. "Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps". Nature Communications, 13():art.n° 115. (2022).
  • Stein, A., Hilken née Thomopoulou, P., Frias, C.. , Hopff, S.M., Varela, P., Wilke, N., Mariappan, A., Neudörfl, J.M., Fedorov, A.Y., Gopalakrishnan, J., Gigant, B., Prokop, A., Schmalz, H.G. "B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner". ACS Omega, 7(3):2591–2603. (2022).
  • Takahashi, D.T., Gadelle, D., Agama, K., Kiselev, E., hang, H., Yab, E., Petrella, S., Forterre, P., Pommier, Y., Mayer, C. "Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states". Nature Communications, 13():art.n° 59. (2022).
  • Goh, B.C., Xiang, X., Lescar, J., Dedon, P.C. "Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA binding site". Journal of Biological Chemistry, 298(2):art.n° 101571. (2022).
  • Hurdiss, D.L., El Kazzi, P., Bauer, L., Papageorgiou, N., Ferron, F.P., Donselaar, T., van Vliet, A.L.W., Shamorkina, T.M., Snijder, J., Canard, B., Decroly, E., Brancale, A., Ben-Mordehai, T.Z., Förster, F., van Kuppeveld, F.J.M., Coutard, B. "Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex". Science Advances, 8(1):art.n° eabj7615. (2022).
  • Mirgaux, M., Leherte, L., Wouters, J. "Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site" International Journal of Tryptophan Research., 14(1-11): (2021).
  • Pietri, G.P., Tontini, M., Brogioni, B., Oldrini, D., Robakiewicz, S., Henriques, P., Calloni, I., Abramova, V., Santini, L., Malić, S., Miklić, K., Lisnic, B., Bertuzzi, S., Unione, L., Balducci, E., de Ruyck, J., Romano, M.R., Jimenez-Barbero, J., Bouckaert, J., Jonjic, S., Lenac Rovis, T., Adamo, R. "Elucidating the Structural and Minimal Protective Epitope of the Serogroup X Meningococcal Capsular Polysaccharide" Frontiers in Molecular Biosciences., 8: art.n° 745360. (2021).
  • Marek, M., Ramos-Morales, E., Picchi-Constante, G.F.A., Bayer, T., Norström, C., Herp, D., Sales-Junior, P.A., Guerra-Slompo, E.P., Hausmann, K., Chakrabarti, A., Shaik, T.B., Merz, A., Troesch, E., Schmidtkunz, K., Goldenberg, S., Pierce, R.J., Mourao, M.M., Jung, M., Schultz, J., Sippl, W., Zanchin, N.I.T., Romier, C. "Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2" Cell Reports., 37(12): art.n° 110129. (2021).
  • Sousa, C.F., Coimbra, J.T.S., Richter, R., Morais-Cabral, J.H., Ramos, M.J., Lehr, C.M., Fernandes, P.A., Gameiro, P. "Exploring the permeation of fluoroquinolone metalloantibiotics across outer membrane porins by combining molecular dynamics simulations and a porin-mimetic in vitro model". Biochimica et Biophysica Acta (BBA) - Biomembranes, 1864():art.n° 183838. (2022).
  • Otero, L.H., Foscaldi, S., Antelo, G.T., Rosano, G.L., Sirigu, S., Klinke, S., Defelipe, L.A., Sánchez-Lamas, M., Battocchio, G., Conforte, V., Vojnov, A.A., Chavas, L.M.G., Goldbaum, F.A., Mroginski, M.A., Rinaldi, J., Bonomi, H.R. "Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level" Science Advances., 7(48): art.n° eabh1097. (2021).