PUBLICATIONS
- Bule, P., Pires, V.M.R., Alves, V.D., Carvalho, A.L., Prates, J.A.M., Ferreira, L.M.A., Smith, S.P., Gilbert, H.J., Noach, I., Bayer, E.A., Najmudin, S., Fontes, C.M.G.A. "Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction" Scientific Reports., 8: art.n° 6987. (2018).
- Capper, M.J., Wright, G.S.A., Barbieri, L., Luchinat, E., Mercatelli, E., McAlary, L., Yerbury, J.J., O’Neill, P.M., Antonyuk, S.V., Banci, L., Hasnain, S. "The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation" Nature Communications., 9: art.n° 1693. (2018).
- Gogoi, P., Seoane, S., Sigueiro, R., Guiberteau, T., Maestro, M.A., Perez-Fernandez, R., Rochel, N., Mouriño, A. "Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists" Journal of Medicinal Chemistry., 61(11): 4928–4937. (2018).
- Nuti, E., Cuffaro, D., Bernardini, E., Camodeca, C., Panelli, L., Chaves, S., Ciccone, L., Tepshi, L., Vera, L., Orlandini, E., Nencetti, S., Stura, E.A., Santos, M.A., Dive, V., Rossello, A. "Development of Thioaryl-based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR and Crystallographic Studies" Journal of Medicinal Chemistry., 61(10): 4421–4435. (2018).
- Fourati, Z., Howard, R.J., Heusser, S.A., Hu, H., Ruza, R.R., Sauguet, L., Lindahl, E., Delarue, M. "Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels" Cell Reports., 23(4): 993–1004. (2018).
- Ahmad, L., Plancqueel, S., Dubosclard, V., Lazar, N., Ghattas, W., Li de la Sierra‐Gallay, I., van Tilbeurgh, H., Salmon, L. "Crystal Structure of Phosphomannose Isomerase from Candida albicans Complexed with 5‐Phospho‐d‐Arabinonhydrazide" FEBS Letters., 592(10): 1667-1680. (2018).
- Pichard-Kostuch, A., Zhang, W., Liger, D., Daugeron, M.C., Letoquart, J., Li de la Sierra-Gallay, I., Forterre, P., Collinet, B., van Tilbeurgh, H., Basta, T. "Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification" RNA., 24(7): 926-938. (2018).
- Badilla, C., Osborne, T.H., Cole, A., Watson, C., Djordjevic, S., Santini, J.M. "A new family of periplasmic-binding proteins that sense arsenic oxyanions" Scientific Reports., 8: art.n° 6282. (2018).
- Powell, J., Mota, F., Steadman, D., Soudy, C., Miyauchi, J.T., Crosby, S., Jarvis, A., Reisinge, T., Winfield, N., Evans, G., Finniear, A., Yelland, T., Chou, Y.T., Chan, A.W.E., O'Leary, A., Cheng, L., Liu, D., Fotinou, N., Milagre, C., Martin, J.F., Jia, H., Frankel, P., Djordjevic, S., Tsirka, S.E., Zachary, I.C., Selwood, D.L. "Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGF#) production in regulatory T-cells" Journal of Medicinal Chemistry., 61(9): 4135-4154. (2018).
- Fournier, J.F., Clary, L., Chambon, S., Dumais, L., Harris, C.S., Millois-Barbuis, C., Pierre, R., Talano, S., Thoreau, E., Aubert, J., Aurelly, M., Bouix-Peter, C., Brethon, A., Chantalat, L., Christin, O., Comino, C., El-Bazbouz, G., Ghilini, A.L., Isabet, T., Lardy, C., Luzy, A.P., Mathieu, C., Mebrouk, K., Orfila, D., Pascau, J., Reverse, K., Roche, D., Rodeschini, V., Hennequin, L.F. "Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne" Journal of Medicinal Chemistry., 61(9): 4030-4051. (2018).