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Nanoscopium is a unique innovative beamline, which is dedicated to fast scanning multimodal and multi-lengthscale (30 nm à 1µm) X-ray imaging.

It offers simultaneous information in a quantitative manner and in the same experimental conditions, in 2D & 3D (tomography) about the elemental composition, chemical speciation and sample morphology.

The NANOSCOPIUM beamline is open for user proposals

The Nanoscopium hard X-ray (5-20 keV) nanoprobe beamline is dedicated to multi-technique X-ray imaging using fast scanning and high spatial resolution. The beamline develops and offers state-of-the-art X-ray nano-imaging and tomography techniques. Indeed, Nanoscopium offers a large portfolio of complementary imaging and spectroscopy methods, also in association to coherent diffraction imaging techniques. The cutting edge multitechnique possibilities available at the beamline pave the way towards quantitative imaging (morphology, elemental composition and chemical speciation) at hierarchical length-scales (30nm – 1µm).

The actually open User Proposal Call of Synchrotron Soleil can be found at

Scanning multi-lengthscale imaging: the spatial resolution is adaptable in the 50 nanometre - 1 micron range

Complex samples with heterogene composition and tiny features of several millimetres samples can be easily studied by this unique zoom-in capability. The results shown below are published in "Highlights 2018 Synchrotron Soleil, page 8",

Calcium (Ca) and Strontium (Sr) distribution of the nacreous layer of a young pearl measured by scanning X-ray fluorescence microscopy. a) Optical microscopy image of the sample. b) Repartition of Calcium (Ca) and Strontium (Sr) within a 1 mm x 2 mm sample area with micrometer spatial resolution. c-d) "Zoom-in" of the Ca distribution within the regions of interest indicated by red rectangles in b and c. c)  Region of  interest chosen from b: size: 50 micron x 50 micron, spatial resolution: 500 nanometre, d) Region of  interest chosen from c: size: 25 micron x 25 micron, spatial resolution: 50 nanometre. 

Coherent Diffraction Imaging: down to 35 nanometre spatial resolution

Sample: Siemens star, energy: 11.2 keV, exposure time: 1 s

Full field absorption and phase contrast X-ray micro-tomography: spatial resolution ~1.2 µm per voxel, acqusition time per tomogram ~5 minutes.

Volume rendering of the absorption contrast tomogram of a foraminifera sample. Full field X-ray micro-tomography techniques are available in combination with scanning multimodal imaging. 

Scientific Opportunities

Earth Sciences & Geobiology

Biocalcification, micro-fossils, paleo-geochemistry, microorganisms in rocks and soils

Aubineau, J. et. al. "Microbially induced potassium enrichment in Paleoproterozoic shales and implications for reverse weathering on early Earth"Nature Communications., 10: art.n° 2670. (2019)

Chi Fru, E et. al. "The rise of oxygen-driven arsenic cycling at ca. 2.48 Ga" Geology., 47(3): 243-246. (2019).

Cuif, J.P., et al. "Revisiting the Organic Template Model through the Microstructural Study of Shell Development in Pinctada margaritifera, the Polynesian Pearl Oyster" Minerals., 8(9): art.n° 370. (2018).

Environmantal Sciences Pollution, bioremediation, climate proxies, paleoclimatology

Metals in cells/tissues: localisation, (mis-)regulation, accumulation, mineralization, biotechnology

Hostachy, S.,et al. "Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins" Chemical Science., 9(19): 4483-4487. (2018).

Material Science Microelectronics, energy storage materials, functional devices, nano-structures, dopants, buried structures
Cultural Heritage Art, history, archaeology and conservation science, pigments, ceramics, resins, fibers.



Andrea Somogyi

Proposals, Scientific & Methodological questions

Office: 01 69 35 96 46, Cell phone: 06 45 47 85 59

Kadda Medjoubi

Proposals, Scientific & Methodological questions

Office: 01 69 35 96 64

Gaëtan Correc

Technical Affairs

Office: 01 69 35 94 42


Beamline Manager
Beamline Scientist
GUO Ruiqiao
LONCLE Antoine

Technical data

Energy range

From 5 KeV to 20 KeV

Energy Resolution

ΔE/E = 10-4 (Si 111) 


Cryo-U18 undulator

Flux @ first optical element

White beam 


Entrance Optics: Mirrors (vertical and horizontal focusing) for prefocusing and harmonics rejection (Si and Rh coating).
Monochromator: Fixed exit Double Crystal Si(111) 
Nanofocusing optics: 


Experimental techniques

Multi-technique and multi-lengthscale scanning X-ray imaging and tomography:

Analytical techniques:

  • X-Ray Fluorescence (XRF) nanoprobe: open for user applications
  • X-ray Absorption Spectroscopy (XANES): open for user applications
  • Full field X-ray microtomography: open for user applications
  • XRF tomography: please contact the beamline scientists
  • Absorption-, Phase-, and Dark Field contrast imaging & tomography: please contact the beamline scientists
  • Coherent Diffraction Imaging (Ptychography): please contact the beamline scientists

Acquisition modes:

  • 2D at multiple lengthscales
  • 3D by full field microtomography tomography & scanning tomography
  • Fast continuous sample scanning (FLYSCAN, multi-detector architecture) with down to ms dwell time/pixel
  • Network architecture: 10 Gbits tailored to the au high data flux produced by the ensemble of detectors (1 TOctets per day)
Sample Environment

Two experimental end-stations, CX2 et CX3, are in exploitation :

CX2 :

  • Nano-focusing optics: FZP
  • Fast multimodal imaging with high spatial resolution (down to 35 nm by Ptychography)

CX3 :

  • Nanofocusing optics: KB (JTEC)
  • Fast multimodal imaging with high spatial resolution (70 nm) and high photon flux providing both very high analytical sensitivity and high resolution for elemental and chemical characterisation
Spatial resolution at sample

CX2 end-station: ~100 x 100 nm2 to 1 x 1 µm2 by FLYSCAN, ~35 x 35 nm2 by Ptychography

CX3 end-station: ~50 x 50 nm2 to 1 x 1 µm2 by FLYSCAN and by step-scan

Flux on sample

CX2 end-station: 108-9 ph/s at 15 keV

CX3 end-station: 1010 ph/s at 15 keV


Single element Si Drift Detector (SDD, Ketek)

Multi-element XRF (4 SDD) (RaySpec)

Fast digital multichannel analyser:

  • 4-channel FALCON (Xia, inc)

Pixel-detector: EIGER 500K

Pixel-detector: JUNGFRAU 500k

2 X-Ray camera with inderect  conversion:

  • Scintillateurs + optics with magnifications of (G2, G5, G10) ORCA FLASH
  • Scintillateur + optics with magnification of (G4) PCO.Edge

Proposed 2D &3D imaging modalities

X-ray Fluorescence Microscopy elemental composition (identification/quantification of all the elements between sulphur and uranium)
X-ray Absorption Spectroscopy  chemical speciation
Absorption, phase and dark field contrast morphology (electron density)
Ptychography (coherent diffraction imaging) high spatial resolution morphology (~35 nm)