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A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase
Publié le 10/11/2017
... Jupin, I., Ayach, M., Jomat, L., Fieulaine, S., Bressanelli, S. "A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase" PLoS Pathogens., 13(11): art.n° e1006714. (2017). ...
New Caspase-1 inhibitor by scaffold hopping into bio-inspired 3D-fragment space
Publié le 10/11/2017
... Brethon, A., Chantalat, L., Christin, O., Clary, L., Fournier, J.F., Gastreich, M., Harris, C., Isabet, T., Pascau, J., Thoreau, E., Roche, D., Rodeschini, V. "New Caspase-1 inhibitor by scaffold hopping into bio-inspired 3D-fragment space" Bioorganic & ...
A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion
Publié le 07/11/2017
... Guardado-Calvo, P., Atkovska, K., Jeffers, S.A., Grau, N., Backovic, M., Pérez-Vargas, J., de Boer, S.M., Tortorici, M.A., Pehau-Arnaude, G., Lepault, J., England, P., Rottier, P.J., Bosch, B.J., Hub, J.S., Rey, F.A. "A glycerophospholipid-specific pocket ...
Mise en évidence d’un auto-assemblage en bicouche de feuillets d’oxyde de graphène à l’interface air-eau
Publié le 06/11/2017
... L’oxyde de graphène est très étudié depuis quelques années, notamment pour son utilisation potentielle comme précurseur du graphène dont les applications sont multiples. Dans ce cadre, la formation de film d’oxyde de graphène de densité et d ...
Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation
Publié le 01/11/2017
... Sulzenbacher, G., Roig-Zamboni, V., Lebrun, R., Guérardel, Y., Murat, D., Mansuelle, P., Yamakawa, N., Quian, X.X., Vincentelli, R., Bourne, Y., Wu, L.F., Alberto, F. "Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella ...
Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles
Publié le 27/10/2017
... Zhu, J., Arena, S., Spinelli, S., Liu, D., Zhang, G., Wei, R., Cambillau, C., Scaloni, A., Wang, G., Pelosi, P. "Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles" PNAS., ...
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)
Publié le 27/10/2017
... Williamson, D.S., Smith, G.P., Acheson-Dossang, P., Bedford, S.T., Chell, V., Chen, I.C., Daechsel, J.C.A., Daniels, Z., David, L., Dokurno, P., Hentzer, M., Herzig, M.C., Hubbard, R.E., Moore, J.D., Murray, J.B., Newland, S., Ray, S.C., Shaw, T., ...
A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast
Publié le 26/10/2017
... Charenton, C., Gaudon Plesse, C., Fourati, Z., Taverniti, V., Back, R., Kolesnikova, O., Séraphin, B., Graille, M. "A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast" PNAS., ...
Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease
Publié le 25/10/2017
... Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Bourne, Y., Parenti, G., Moracci, M., Sulzenbacher, G. "Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease" Nature Communications., 8: ...
Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics
Publié le 25/10/2017
... Douzi, B., Trinh, T.T.N., Michel-Souzy, S., Desmyter, A., Ball, G., Barbier, P., Kostad, A., Durand, E., Forest, K.T., Cambillau, C., Roussel, A., Voulhoux, R. "Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain ...