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The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation
Publié le 17/02/2026
... C. Michail, , J. Berthelet, , A. E. Mechaly, , L.-C.Bui, , H. Yang, , D.Cai, , A. Al Mahi, , A. Xie, , V. Bisio, , V. Sirri, , J.-M. Dupret, , F. Guidez, , X. Xu, , N. Joly, , L. Regad, , M. Viguier, , F. Deshayes, , N. Dulphy, , M. R. Green, , A. Haouz,, ...
New fluoxetine analogues as anti-enterovirus agents targeting 2C protein
Publié le 13/02/2026
... Khemiri, S., Faucher, M.O., Bourg, S., Attoumani-Madi, S., Yaacoub, C., Touret, F., Farag, M., Fermiana Vitorino, M., Bonnet c, Vanelle, P., Aci-Seche, S., Coutard, B., Barral, K. "New fluoxetine analogues as anti-enterovirus agents targeting 2C protein". ...
Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis
Publié le 13/02/2026
... Carloni, G., Gaday, Q., Megrian, D., Petit, J., Martinez, M., Sogues, A., Ben Assaya, M., Kakonyi, M., Haouz, A., Alzari, P.M., Wehenkel, A.M. "Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis". ...
Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach
Publié le 13/02/2026
... Valderrama, K., Horlacher, O., Publicola, G., Eisenring, P., Kienle, M., Boarbi, S., Kiass, M., Korduláková, J., Chatagnon, J., Piveteau, C. , Leroux, F., Savková, K., Záhorszká, M., Cantrelle, F.X. , Lherbet, C., Mourey, L., Mikušová, K., Mathys, V., ...
First crystal structure of an adduct formed upon reaction of a vanadium compound with human serum transferrin
Publié le 21/01/2026
... Banneville, A.S., Lucignano, R., Paolillo, M., Cuomo, V., Chino, M., Ferraro, G., Picone, D., Garribba, E., Cornaciu-Hoffmann, I., Pica, A., Merlino, A. "First crystal structure of an adduct formed upon reaction of a vanadium compound with human serum ...
SH3 domains selectively activate the PI3 kinase through non-conventional tertiary contacts
Publié le 20/01/2026
... Aljedani, S.S., Sandholu, A., Aldehaiman, A., Alharbi, S., Mak, V.C.Y., Wu, H., Wang, P., Momin, A.A., Singh, U., Lugari, A., Jaremko, L., Jaremko, M., Morelli, X., Backer, J.W., Ladbury, J.E., Nowakowski, M., Cheung, L.W.T., Arold, S.T. "SH3 domains ...
Quantitative mapping of methionine sensitivity to oxidation in the copper-bound PcuC chaperone
Publié le 19/01/2026
... Tarrago, L., Molinelli, L., Belghazi, M., Tribout, M., Lemaire, D., Legrand, P., Grosse, S., Pignol, D., Sabaty, M., Tron, T., Arnoux, P. "Quantitative mapping of methionine sensitivity to oxidation in the copper-bound PcuC chaperone".
Redox ...
Genome anchoring, retention, and release by neck proteins of Staphylococcus phage 812
Publié le 17/01/2026
... Cieniková, Z., Nováček, J., Šiborová, M., Popelářová, B., Füzik, T., Botka, T., Benešík, M., Bárdy, P., Pantůček, R., Plevka, P. "Genome anchoring, retention, and release by neck proteins of Staphylococcus phage 812".
Communications Biology, ...
Plant UBX Domain-Containing Proteins Use Distinct Strategies to Stably Engage the Unfoldase CDC48A
Publié le 13/01/2026
... Zhang, J., Wang, J., Sandholu, A., Hameed , U.F.S., Arold, S.T. "Plant UBX Domain-Containing Proteins Use Distinct Strategies to Stably Engage the Unfoldase CDC48A". Plant and Cell Physiology., on line first (12/01/2026): (2026). ...
Synergistic Action of Crystallophore and Imaging-Crystallophore Enhances the Production and Imaging of Protein Crystals
Publié le 13/01/2026
... Roux, M., Roux, A., Boukéké-Lespulier, T., Riobé, F., Chapelle, C., Foos, N., Dumont, E., Girard, E., Gillet, N., Maury, O. "Synergistic Action of Crystallophore and Imaging-Crystallophore Enhances the Production and Imaging of Protein Crystals". ...