RECHERCHER
Résultats de la recherche ""
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1
Publié le 17/10/2018
... Bloch, Y., Bouchareychas, L., Merceron, R., Składanowska,K., Van den Bossche,L., Detry,S., Govindarajan,S., Elewaut,D., Haerynck,F., Dullaers,M., Adamopoulos,I.E., Savvides, S.N. "Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate ...
Soutenons la lutte contre le cancer avec Blandine ! - Jour 2 du Raid
Publié le 16/10/2018
... Une pluie de photos de Blandine et ses coéquipières pour ce deuxième jour d'épreuves ! ...
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining
Publié le 09/10/2018
... Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, ...
Radiothérapie : Pour défendre l’ADN, les protéines partent en quête de l’anneau
Publié le 05/10/2018
... Pour comprendre pourquoi certaines cellules cancéreuses parviennent à résister à la radiothérapie, une équipe internationale de chercheurs a recouru à la cristallographie pour « photographier » les premiers instants du ballet ...
Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in M. tuberculosis
Publié le 05/10/2018
... Nguyen, P.C., Nguyen, V.S., Martin, B.P., Fourquet, P., Luc Camoin, L., Spilling, C.D., Cavalier, J.F., Cambillau, C., Canaan, S. "Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in ...
Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis
Publié le 02/10/2018
... Dorival, J., Risser, F., Jacob, C., Colin, S., Dräger, G., Paris, C., Chagot, B., Kirschning, A., Gruez, A., Weissman, K. J. "Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis" Nature Communications., 9: art.n° 3998. ...
Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state
Publié le 01/10/2018
... Rinaldi, J., Fernández, I., Poth, L.M., Shepard, W.E., Savko, M., Goldbaum, F.A., Klinke, S. "Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state" ...
Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins
Publié le 01/10/2018
... Reichenbach , T., Kalyani , D., Gandini, R., Svartström, O., Aspeborg , H., Divne, C. "Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins" PLoS One., 13(9): ...
Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E
Publié le 01/10/2018
... Bandyra, K.J., Wandzik, J.M., Luisi, B.F. "Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E" Molecular Cell., 72(2): 275-285.e4. (2018). ...
Discovery of N‑(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)‑1H‑1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
Publié le 26/09/2018
... Kettle, J.G., Anjum, R., Barry, E., Bhavsar, D., Brown, C., Boyd, S., Campbell, A., Goldberg, K., Grondine, M., Guichard, S., Hardy, C.J., Hunt, T., Jones, R.D.O., Xiuwei Li, X., Moleva, O., Ogg, D., Overman, R.C., Packer, M.J., Pearson, S., Schimpl, M., ...