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Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels
Publié le 27/04/2018
... Fourati, Z., Howard, R.J., Heusser, S.A., Hu, H., Ruza, R.R., Sauguet, L., Lindahl, E., Delarue, M. "Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels" Cell Reports., 23(4): 993 ...
Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification
Publié le 25/04/2018
... Pichard-Kostuch, A., Zhang, W., Liger, D., Daugeron, M.C., Letoquart, J., Li de la Sierra-Gallay, I., Forterre, P., Collinet, B., van Tilbeurgh, H., Basta, T. "Structure-function analysis of Sua5 protein reveals novel functional motifs required for the ...
Crystal Structure of Phosphomannose Isomerase from Candida albicans Complexed with 5‐Phospho‐d‐Arabinonhydrazide
Publié le 25/04/2018
... Ahmad, L., Plancqueel, S., Dubosclard, V., Lazar, N., Ghattas, W., Li de la Sierra‐Gallay, I., van Tilbeurgh, H., Salmon, L. "Crystal Structure of Phosphomannose Isomerase from Candida albicans Complexed with 5‐Phospho‐d‐Arabinonhydrazide" FEBS Letters., ...
A new family of periplasmic-binding proteins that sense arsenic oxyanions
Publié le 24/04/2018
... Badilla, C., Osborne, T.H., Cole, A., Watson, C., Djordjevic, S., Santini, J.M. "A new family of periplasmic-binding proteins that sense arsenic oxyanions" Scientific Reports., 8: art.n° 6282. (2018). ...
Entrée du virus de la stomatite vésiculaire dans les cellules hôtes : Deux nouvelles structures moléculaires résolues
Publié le 18/04/2018
... Le virus de la stomatite vésiculaire (VSV) est un virus enveloppé qui peut infecter les insectes, les bovins, les chevaux et les porcs. Chez les mammifères, sa capacité à infecter et tuer les cellules tumorales, tout en épargnant les cellules ...
Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGF#) production in regulatory T-cells
Publié le 14/04/2018
... Powell, J., Mota, F., Steadman, D., Soudy, C., Miyauchi, J.T., Crosby, S., Jarvis, A., Reisinge, T., Winfield, N., Evans, G., Finniear, A., Yelland, T., Chou, Y.T., Chan, A.W.E., O'Leary, A., Cheng, L., Liu, D., Fotinou, N., Milagre, C., Martin, J.F., Jia ...
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne
Publié le 14/04/2018
... Fournier, J.F., Clary, L., Chambon, S., Dumais, L., Harris, C.S., Millois-Barbuis, C., Pierre, R., Talano, S., Thoreau, E., Aubert, J., Aurelly, M., Bouix-Peter, C., Brethon, A., Chantalat, L., Christin, O., Comino, C., El-Bazbouz, G., Ghilini, A.L., ...
Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
Publié le 11/04/2018
... Hu, H., Nemecz, A., Van Renterghem, C., Fourati, Z., Sauguet, L., Corringer, P.J., Delarue, M. "Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation" PNAS., 115(17): E3959-E3968. ...
Tuning the Kondo resonance in two-dimensional lattices of cerium molecular complexes
Publié le 10/04/2018
... Granet, J., Sicot, M., Kierren, B., Lamare, S., Cherioux, F., Baudelet, F., Fagot-Revurat, Y., Moreau, L., Malterre, D. "Tuning the Kondo resonance in two-dimensional lattices of cerium molecular complexes" Nanoscale., 10(19): 9123-9132. (2018). ...
Lytic xylan oxidases from wood-decay fungi unlock biomass degradation
Publié le 10/04/2018
... Couturier, M., Ladevèze, S., Sulzenbacher, G., Ciano, L., Fanuel, M., Moreau, C., Villares, A., Cathala, B., Chaspoul, F., Frandsen, K.E., Labourel, A., Herpoël-Gimbert, I., Grisel, S., Haon, M., Lenfant, N., Rogniaux, H., Ropartz, D., Davies, G.J., Rosso ...