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Mécanisme moléculaire de la régulation du cholestérol LDL
Publié le 15/03/2023
... Dans une étape cruciale vers la compréhension des mécanismes relatifs aux maladies cardiovasculaires et à certains cancers, une équipe de recherche a réussi une première mondiale : trouver le mécanisme moléculaire par lequel la protéine PCSK9 ...
Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C β-Lactamases
Publié le 10/03/2023
... Cawez, F., Mercuri, P.S., Morales-Yãnez, F.J., Rita Maalouf, R., Marylène Vandevenne, M., Frederic Kerff, F., Virginie Guérin, V., Jacques Mainil, J., Thiry, D., Saulmont, M., Vanderplasschen, A., Lafaye, P., Aymé, G., Bogaerts, P., Dumoulin, M., Galleni, ...
The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG
Publié le 07/03/2023
... Weiß, M., Giacomelli, G., Ben Assaya, M., Grundt, F., Haouz, A., Peng, F., Petrella, S., Wehenkel, A.M., Bramkamp, M. "The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG" Nucleic Acids Research., 51(7): 3288–3306. ...
The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells
Publié le 07/03/2023
... Fernández, I., Dynesen, L.T., Coquin, Y., Pederzoli, R., Brun, D., Haouz, A., Gessain, A., Rey, F.A., Buseyne, F., Backovic, M. "The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells" Nature ...
YbiB: a novel interactor of the GTPase ObgE
Publié le 07/03/2023
... Deckers, B., Vercauteren, S., De Kock, V., Martin, C., Lazar, T., Herpels, P., Dewachter, L., Verstraeten, N., Peeters, E., Ballet, S., Michiels, J., Galicia, C., Versées, W. "YbiB: a novel interactor of the GTPase ObgE" Nucleic Acids Research., 51(7): ...
Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization
Publié le 02/03/2023
... Roy, A., Chan Mine, E., Gaifas, L., Leyrat, C., Volchkova, V.A., Baudin, F., Martinez-Gil, L., Volchkov, V.E., Karlin, D.G., Bourhis, J.M., Jamin, M. "Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization" Biomolecules. ...
Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis
Publié le 02/03/2023
... Yogavel, M., Bougdour, A., Mishra, S., Malhotra, N., Chhibber-Goel, J., Bellini, V., Harlos, K., Laleu, B., Hakimi, M.A., Sharma, A. "Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis" PLoS ...
Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7
Publié le 28/02/2023
... Prolič-Kalinšek, M., Volkov, A.N., Hadži,S., Van Dyck,J., Bervoets,I., Charlier, D., Loris, R. "Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7" Acta ...
Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4
Publié le 25/02/2023
... Gajendran, C., Fukui, S., Sadhu, N.M., Zainuddin, M., Rajagopal, S., Gosu, R., Gutch, S., Fukui, S., Sheehy, C.E., Long Chu, L., Vishwakarma, S., Jeyaraj, D. A., Hallur, G., Wagner, D.D., Sivanandhan, D. "Alleviation of arthritis through prevention of ...
Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein
Publié le 23/02/2023
... Hellert, J., Aebischer, A., Haouz, A., Guardado-Calvo, P., Reiche, S., Beer, M., Rey, F.A. "Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein" Cell Reports., 42(3): art.n° 112142. (2023). ...