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Conformational variability in the D2 loop of Plasmodium Apical Membrane antigen 1
Publié le 18/09/2024
... Saul, F.A., Vulliez-Le Normand, B., Boes, A., Spiegel, S., Kocken, C.H.M., Faber, B.W., Bentley, G.A. "Conformational variability in the D2 loop of Plasmodium Apical Membrane antigen 1" Journal of Structural Biology: X., 10: art.n° 100110. (2024). ...
The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains
Publié le 18/09/2024
... Gomes, M.V., Landwerlin, P., Diebold-Durand, M.L., Shaik, T.B., Durand, A., Troesch, E., Weber, C., Brillet, K., Lemée, M.V., Decroos, C., Dulac, L., Antony, P., Watrin, E., Ennifar, E., Golzio, C., Romier, C. "The cohesin ATPase cycle is mediated by ...
Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models
Publié le 18/09/2024
... Dejoux, A., Zhu, Q., Ganneau, C., Richard-Le Goff, O., Godon, O., Lemaitre, J., Relouzat, F., Huetz, F., Sokal, A., Vandenberghe, A., Pecalvel, C., Hunault, L., Derenne, T., Gillis, C.M., Iannascoli, B., Wang, Y., Rose, T., Mertens, C., Nicaise-Roland, P. ...
The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution
Publié le 18/09/2024
... Chazot, A., Zimberger, C., Feracci, M., Moussa, A., Good, S., Sommadossi, J.P., Alvarez, K., Ferron, F., Canard, B. "The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution" PloS Biology., 22(8): art.n° ...
Comment le Coronavirus HKU1 force la porte d’entrée de nos cellules
Publié le 23/08/2024
... Des scientifiques de l’Institut Pasteur ont mis à jour les endroits précis des cellules respiratoires où se fixe le coronavirus HKU1, permettant ainsi d’expliquer en détail le mécanisme d’infection mis en œuvre. Une découverte qui a permis d ...
Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody
Publié le 23/08/2024
... Pinto Torres, J.E., Claes, M., Hendrickx, R., Yuan, M., Smiejkowska, N., Van Wielendaele, P., De Winter, H., Muyldermans, S., Michels, P.A., Walkinshaw, M.D., Versées, W., Caljon, G., Magez, S., Sterckx, Y.G.J. "Allosteric inhibition of trypanosomatid ...
Unveiling glomerular gold in oxalate nephropathy
Publié le 21/08/2024
... Gibier, J.B., Tang, E., Bazin, D., Medjoubi, K., Somogyi, A., Daudon, M., Vrigneaud, L., Letavernier, E. "Unveiling glomerular gold in oxalate nephropathy" Kidney International., 106(3): art.n° 543. (2024). ...
Twin Peaks: Interrogating Otolith Pairs to See Whether They Keep Their Stories Straight
Publié le 06/08/2024
... Lord, C., Berland, S., Haÿ, V., Medjoubi, K., Keith, P. "Twin Peaks: Interrogating Otolith Pairs to See Whether They Keep Their Stories Straight" Crystals., 14(8): art.n° 705. (2024). ...
Bioinformatic, Enzymatic, and Structural Characterization of Trichuris suis Hexosaminidase HEX-2
Publié le 29/07/2024
... Dutkiewicz, Z., Varrot, A., Breese, K.J., Stubbs, K.A., Nuschy, L., Adduci, I., Paschinger, K., Wilson, I.B.H. "Bioinformatic, Enzymatic, and Structural Characterization of Trichuris suis Hexosaminidase HEX-2" Biochemistry., 53(15): 1941-1954. (2024). ...
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy
Publié le 24/07/2024
... Hartman, J.J., Hwee, D.T., Robert-Paganin, J., Chuang, C., Chin, E.R., Edell, S., Lee, K.H., Madhvani, R., Paliwal, P., Pernier, J., Sarkar, S.S., Schaletzky, J., Schauer, K., Taheri, K.D., Wang, J., Wehri, E., Wu, Y., Houdusse, A., Morgan, B.P., Malik, F ...