RECHERCHER
Résultats de la recherche ""
Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis
Publié le 22/02/2025
... Schulze, M.S.E.D., Scholz, D., Jnoff, E., Hall, A., Melin, J., Sands, Z.A., Rodriguez, E., Andre, V.M. "Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis" ChemMedChem., 19(7): art.n° e202300548. (2024). ...
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors
Publié le 22/02/2025
... Mfuh, A.M., Boerth, J.A., Bommakanti, G., Chan, C., Chinn, A.J., Code, E., Fricke, P.J., Giblin, K.A., Gohlke, A., Hansel, C., Hariparsad, N., Hughes, S.J., Jin, M., Kantae, V., Kavanagh, S.L., Lamb, M.L., Lane, J., Moore, R., Puri, T., Quinn, T.R., Reddy ...
Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Publié le 22/02/2025
... Cellupica, E., Gaiassi, A., Rocchio, I., Rovelli, G., Pomarico, R., Sandrone, G., Caprini, G., Cordella, P., Cukier, C., Fossati, G., Marchini, M., Bebel, A., Airoldi, C., Palmioli, A., Stevenazzi, A., Steinkuhler, C., Vergani, B. "Mechanistic and ...
Structural insights into tecovirimat antiviral activity and poxvirus resistance
Publié le 14/02/2025
... Vernuccio, R., Martínez León, A., Poojari, C.S., Buchrieser, J., Selverian, C.N., Jaleta, Y., Meola, A., Guivel-Benhassine, F., Porrot, F., Haouz, A., Chevreuil, M., Raynal, B., Mercer, J., Simon-Loriere, S., Chandran, K., Schwartz, O., Hub, J.S., ...
Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair
Publié le 11/02/2025
... Claustre, A., Malige, M., Macheton, M., Combaret, L., Lefai, E., Fafournoux, P., Taillandier, D., Henri, J., Polge, C. "Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair" ...
Effect of Compression on Microstructure and Fluid Transport Properties on an Electrospun Gas Diffusion Layer for PEMFC from 3D High-Resolution Imaging
Publié le 10/02/2025
... Roussillo--David de Beaufort, B., Fouda-Onana, F., Ducros, J.B., David, T., Scheel, M., Serre, G., Pauchet, J., Prat, M. "Effect of Compression on Microstructure and Fluid Transport Properties on an Electrospun Gas Diffusion Layer for PEMFC from 3D High ...
RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases
Publié le 07/02/2025
... Coste, F., Mishra, A., Chapuis, C., Mance, L., Pukało,Z., Bigot,N., Goffinont, S., Gaudon, V., Garnier, N., Talhaoui, I., Castaing, B., Huet, S., Suskiewicz, M.J. "RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases" FEBS ...
Le sens du toucher, si important mais si mal connu
Publié le 05/02/2025
... Complétant la vue, l’ouïe, le goût et l’odorat, le toucher est un sens discret mais essentiel. Il nous permet par exemple de percevoir le monde qui nous entoure, de manipuler des objets avec dextérité et même de communiquer des émotions. ...