PROXIMA-1
Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates
Référence
T. Arnaud,, C. Tatol,, J. M. Devos,, L. Gajdos,, S. Vidal,, M. Korsak,, A. Varrot,, M. Wimmerova,, S. Feuillastre,, M. P. Blakeley,, A. Imberty "Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates". Chemistry Europe, 4(3):e202500424. (2026).
Année de publication
2026
Auteurs
T. Arnaud,
C. Tatol,
J. M. Devos,
L. Gajdos,
S. Vidal,
M. Korsak,
A. Varrot,
M. Wimmerova,
S. Feuillastre,
M. P. Blakeley,
A. Imberty
Lignes de lumière
rec-number
13014
Référence anonyme
T. Arnaud,, C. Tatol,, J. M. Devos,, L. Gajdos,, S. Vidal,, M. Korsak,, A. Varrot,, M. Wimmerova,, S. Feuillastre,, M. P. Blakeley,, A. Imberty "Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates".
Chemistry Europe,
4(3):e202500424.
(2026).
Type de publication
Date
Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis
Référence
Z. Edoo,, C. Grosse,, T. Maitre,, R. Frita,, A. Chauffour,, L. Fournier Le Ray,, A. Godmer,, A. Aubry,, M. Bourotte,, R. Antoine,, L. Tawk,, S. Slupek,, V. Trebosc,, B. Schellhorn,, A. Dreneau,, L. Hofmann,, C. Kemmer,, S. Lociuro,, G. E. Dale,, F. Jung,, E. Pérez-Herrán,, A. Mendoza,, M. J. Rebollo López,, S. Ghidelli-Disse,, T. Werner,, L. Ballell,, D. Barros-Aguirre,, V. Mathys,, K. Soetaert,, V. Megalizzi,, R. Wintjens,, M. Gitzinger,, B. Deprez,, N. Veziris,, M. J. Remuiñán,, N. Willand,, M. Pieren,, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis". Nature Communications, online first (07/04/2026)():. (2026).
Année de publication
2026
Auteurs
Z. Edoo,
C. Grosse,
T. Maitre,
R. Frita,
A. Chauffour,
L. Fournier Le Ray,
A. Godmer,
A. Aubry,
M. Bourotte,
R. Antoine,
L. Tawk,
S. Slupek,
V. Trebosc,
B. Schellhorn,
A. Dreneau,
L. Hofmann,
C. Kemmer,
S. Lociuro,
G. E. Dale,
F. Jung,
E. Pérez-Herrán,
A. Mendoza,
M. J. Rebollo López,
S. Ghidelli-Disse,
T. Werner,
L. Ballell,
D. Barros-Aguirre,
V. Mathys,
K. Soetaert,
V. Megalizzi,
R. Wintjens,
M. Gitzinger,
B. Deprez,
N. Veziris,
M. J. Remuiñán,
N. Willand,
M. Pieren,
A. R. Baulard
Lignes de lumière
rec-number
13064
Référence anonyme
Z. Edoo,, C. Grosse,, T. Maitre,, R. Frita,, A. Chauffour,, L. Fournier Le Ray,, A. Godmer,, A. Aubry,, M. Bourotte,, R. Antoine,, L. Tawk,, S. Slupek,, V. Trebosc,, B. Schellhorn,, A. Dreneau,, L. Hofmann,, C. Kemmer,, S. Lociuro,, G. E. Dale,, F. Jung,, E. Pérez-Herrán,, A. Mendoza,, M. J. Rebollo López,, S. Ghidelli-Disse,, T. Werner,, L. Ballell,, D. Barros-Aguirre,, V. Mathys,, K. Soetaert,, V. Megalizzi,, R. Wintjens,, M. Gitzinger,, B. Deprez,, N. Veziris,, M. J. Remuiñán,, N. Willand,, M. Pieren,, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis".
Nature Communications,
online first (07/04/2026)():.
(2026).
Type de publication
Date
Subcellular reorganization upon phage infection reveals stepwise assembly of viral particles from membrane-associated precursors
Référence
S. Corroyer-Dulmont,, A. Labarde,, V. Pražák,, L. M. Godinho,, C. Masson,, P. Legrand,, K. Grünewald,, P. Tavares,, R. J. Quemin "Subcellular reorganization upon phage infection reveals stepwise assembly of viral particles from membrane-associated precursors". Nature Communications, online first (02/04/2026)():. (2026).
Année de publication
2026
Auteurs
S. Corroyer-Dulmont,
A. Labarde,
V. Pražák,
L. M. Godinho,
C. Masson,
P. Legrand,
K. Grünewald,
P. Tavares,
R. J. Quemin
Lignes de lumière
rec-number
13065
Référence anonyme
S. Corroyer-Dulmont,, A. Labarde,, V. Pražák,, L. M. Godinho,, C. Masson,, P. Legrand,, K. Grünewald,, P. Tavares,, R. J. Quemin "Subcellular reorganization upon phage infection reveals stepwise assembly of viral particles from membrane-associated precursors".
Nature Communications,
online first (02/04/2026)():.
(2026).
Type de publication
Date
The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms
Référence
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms". Nucleic Acids Research, 54(6):. (2026).
Année de publication
2026
Auteurs
Z. Marouf,
C. Tellier-Lebegue,
M. Glousieau,
N. Morellet,
P. Cuniasse,
A. Bourand-Plantefol,
S. Plancqueel,
I. Mahmoudi,
J. Andreani,
P. Legrand,
V. Ropars,
R. Ruedas,
L.-F.Hermouet,
M. Moutiez,
N. Nhiri,
M. Fonvielle,
S. Bressanelli,
T. Katoh,
P. Fernandez Varela,
E. Lescop,
J.-B. Charbonnier,
M. Gondry
Lignes de lumière
rec-number
13068
Référence anonyme
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms".
Nucleic Acids Research,
54(6):.
(2026).
Type de publication
Date
Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML
Référence
G. Dutheuil,, K. Oukoloff,, F. Lenoir,, J. Korac,, M. El Bousmaqui,, N. Probst,, A. Lapin,, G. Nakhabina,, N. Parmentier,, C. Sorlet,, G. L. Fraser "Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML". Journal of Medicinal Chemistry, 68(8):9585-9602. (2026).
Année de publication
2026
Auteurs
G. Dutheuil,
K. Oukoloff,
F. Lenoir,
J. Korac,
M. El Bousmaqui,
N. Probst,
A. Lapin,
G. Nakhabina,
N. Parmentier,
C. Sorlet,
G. L. Fraser
Lignes de lumière
rec-number
13098
Référence anonyme
G. Dutheuil,, K. Oukoloff,, F. Lenoir,, J. Korac,, M. El Bousmaqui,, N. Probst,, A. Lapin,, G. Nakhabina,, N. Parmentier,, C. Sorlet,, G. L. Fraser "Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML".
Journal of Medicinal Chemistry,
68(8):9585-9602.
(2026).
Type de publication
Date
Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure
Référence
R. Nermont,, S. Oueslati,, M. Aumont-Nicaise,, P. Retailleau,, B. I. Iorga,, T. Naas "Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure". Antimicrobial Agents and Chemotherapy, online first (29/04/2026)():. (2026).
Année de publication
2026
Auteurs
R. Nermont,
S. Oueslati,
M. Aumont-Nicaise,
P. Retailleau,
B. I. Iorga,
T. Naas
Lignes de lumière
rec-number
13112
Référence anonyme
R. Nermont,, S. Oueslati,, M. Aumont-Nicaise,, P. Retailleau,, B. I. Iorga,, T. Naas "Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure".
Antimicrobial Agents and Chemotherapy,
online first (29/04/2026)():.
(2026).
Type de publication
Date
The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation
Référence
C. Michail, , J. Berthelet, , A. E. Mechaly, , L.-C.Bui, , H. Yang, , D.Cai, , A. Al Mahi, , A. Xie, , V. Bisio, , V. Sirri, , J.-M. Dupret, , F. Guidez, , X. Xu, , N. Joly, , L. Regad, , M. Viguier, , F. Deshayes, , N. Dulphy, , M. R. Green, , A. Haouz,, F. R. Lima "The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation". Journal of Biological Chemistry, 302(3):111259. (2026).
Année de publication
2026
Auteurs
C. Michail,
J. Berthelet,
A. E. Mechaly,
L.-C.Bui,
H. Yang,
D.Cai,
A. Al Mahi,
A. Xie,
V. Bisio,
V. Sirri,
J.-M. Dupret,
F. Guidez,
X. Xu,
N. Joly,
L. Regad,
M. Viguier,
F. Deshayes,
N. Dulphy,
M. R. Green,
A. Haouz,
F. R. Lima
Lignes de lumière
rec-number
12901
Référence anonyme
C. Michail, , J. Berthelet, , A. E. Mechaly, , L.-C.Bui, , H. Yang, , D.Cai, , A. Al Mahi, , A. Xie, , V. Bisio, , V. Sirri, , J.-M. Dupret, , F. Guidez, , X. Xu, , N. Joly, , L. Regad, , M. Viguier, , F. Deshayes, , N. Dulphy, , M. R. Green, , A. Haouz,, F. R. Lima "The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation".
Journal of Biological Chemistry,
302(3):111259.
(2026).
Type de publication
Date
New fluoxetine analogues as anti-enterovirus agents targeting 2C protein
Référence
Khemiri, S., Faucher, M.O., Bourg, S., Attoumani-Madi, S., Yaacoub, C., Touret, F., Farag, M., Fermiana Vitorino, M., Bonnet c, Vanelle, P., Aci-Seche, S., Coutard, B., Barral, K. "New fluoxetine analogues as anti-enterovirus agents targeting 2C protein". European Journal of Inorganic Chemistry, 306():118621. (2026).
Année de publication
2026
Auteurs
Khemiri, S.
Faucher, M.O.
Bourg, S.
Attoumani-Madi, S.
Yaacoub, C.
Touret, F.
Farag, M.
Fermiana Vitorino, M.
Bonnet c
Vanelle, P.
Aci-Seche, S.
Coutard, B.
Barral, K.
Lignes de lumière
rec-number
12889
Référence anonyme
Khemiri, S., Faucher, M.O., Bourg, S., Attoumani-Madi, S., Yaacoub, C., Touret, F., Farag, M., Fermiana Vitorino, M., Bonnet c, Vanelle, P., Aci-Seche, S., Coutard, B., Barral, K. "New fluoxetine analogues as anti-enterovirus agents targeting 2C protein".
European Journal of Inorganic Chemistry,
306():118621.
(2026).
Type de publication
Date
Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis
Référence
Carloni, G., Gaday, Q., Megrian, D., Petit, J., Martinez, M., Sogues, A., Ben Assaya, M., Kakonyi, M., Haouz, A., Alzari, P.M., Wehenkel, A.M. "Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis". MBio, 17(3):e03700-25. (2026).
Année de publication
2026
Auteurs
Carloni, G.
Gaday, Q.
Megrian, D.
Petit, J.
Martinez, M.
Sogues, A.
Ben Assaya, M.
Kakonyi, M.
Haouz, A.
Alzari, P.M.
Wehenkel, A.M.
Lignes de lumière
rec-number
12890
Référence anonyme
Carloni, G., Gaday, Q., Megrian, D., Petit, J., Martinez, M., Sogues, A., Ben Assaya, M., Kakonyi, M., Haouz, A., Alzari, P.M., Wehenkel, A.M. "Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis".
MBio,
17(3):e03700-25.
(2026).
Type de publication
Date
Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach
Référence
Valderrama, K., Horlacher, O., Publicola, G., Eisenring, P., Kienle, M., Boarbi, S., Kiass, M., Korduláková, J., Chatagnon, J., Piveteau, C. , Leroux, F., Savková, K., Záhorszká, M., Cantrelle, F.X. , Lherbet, C., Mourey, L., Mikušová, K., Mathys, V., Aichholz, R., Maveyraud, L., Altmann, K.H. , Hartkoorn, R.C. "Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach". Journal of Medicinal Chemistry, 69(3):2496-2508. (2026).
Année de publication
2026
Auteurs
Valderrama, K.
Horlacher, O.
Publicola, G.
Eisenring, P.
Kienle, M.
Boarbi, S.
Kiass, M.
Korduláková, J.
Chatagnon, J.
Piveteau, C.
Leroux, F.
Savková, K.
Záhorszká, M.
Cantrelle, F.X.
Lherbet, C.
Mourey, L.
Mikušová, K.
Mathys, V.
Aichholz, R.
Maveyraud, L.
Altmann, K.H.
Hartkoorn, R.C.
Lignes de lumière
rec-number
12888
Référence anonyme
Valderrama, K., Horlacher, O., Publicola, G., Eisenring, P., Kienle, M., Boarbi, S., Kiass, M., Korduláková, J., Chatagnon, J., Piveteau, C. , Leroux, F., Savková, K., Záhorszká, M., Cantrelle, F.X. , Lherbet, C., Mourey, L., Mikušová, K., Mathys, V., Aichholz, R., Maveyraud, L., Altmann, K.H. , Hartkoorn, R.C. "Optimizing the Antibiotic Potency and Metabolic Stability of Pyridomycin Using a Semisynthetic Approach".
Journal of Medicinal Chemistry,
69(3):2496-2508.
(2026).
Type de publication
Date