PROXIMA-2A
Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections
Référence
M. Fournier, M. Vanderkerken, K. Dorgham, P. Bastard, O. Ahouzi, S. Duquerroy, N. Khanh Nguyen, M. Broutin, M. Charlet, A. Vandenberghe, P. Van Endert, L. Bizien, O. Da Mata-Jardin, A. Ferriño-Iriarte, A. Haouz, T. Belmondo, S. Hüe, A. Borghesi, C. Rodríguez-Gallego, D. C. Vinh, M. Mahévas "Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections". Cell, online first (06/05/2026)():. (2026).
Année de publication
2026
Auteurs
M. Fournier
M. Vanderkerken
K. Dorgham
P. Bastard
O. Ahouzi
S. Duquerroy
N. Khanh Nguyen
M. Broutin
M. Charlet
A. Vandenberghe
P. Van Endert
L. Bizien
O. Da Mata-Jardin
A. Ferriño-Iriarte
A. Haouz
T. Belmondo
S. Hüe
A. Borghesi
C. Rodríguez-Gallego
D. C. Vinh
M. Mahévas
Lignes de lumière
rec-number
13170
Référence anonyme
M. Fournier, M. Vanderkerken, K. Dorgham, P. Bastard, O. Ahouzi, S. Duquerroy, N. Khanh Nguyen, M. Broutin, M. Charlet, A. Vandenberghe, P. Van Endert, L. Bizien, O. Da Mata-Jardin, A. Ferriño-Iriarte, A. Haouz, T. Belmondo, S. Hüe, A. Borghesi, C. Rodríguez-Gallego, D. C. Vinh, M. Mahévas "Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections".
Cell,
online first (06/05/2026)():.
(2026).
Type de publication
Date
NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes
Référence
L. Delcourte,, C. Sanchez,, E. Morvan,, M. Berbon,, A. Grélard,, C. Saragaglia,, T. Dakhli,, S. Thore,, B. Bardiaux,, B. Habenstein,, B. Kauffmann,, S. J. Saupe,, A. Loquet "NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes". Biomolocular NMR Assigments, 18():159-164. (2024).
Année de publication
2024
Auteurs
L. Delcourte,
C. Sanchez,
E. Morvan,
M. Berbon,
A. Grélard,
C. Saragaglia,
T. Dakhli,
S. Thore,
B. Bardiaux,
B. Habenstein,
B. Kauffmann,
S. J. Saupe,
A. Loquet
Lignes de lumière
rec-number
12998
Référence anonyme
L. Delcourte,, C. Sanchez,, E. Morvan,, M. Berbon,, A. Grélard,, C. Saragaglia,, T. Dakhli,, S. Thore,, B. Bardiaux,, B. Habenstein,, B. Kauffmann,, S. J. Saupe,, A. Loquet "NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes".
Biomolocular NMR Assigments,
18():159-164.
(2024).
Type de publication
Date
Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin
Référence
S. Thore,, F. Raoelijaona,, V. Talenton,, S. Fribourg,, C. D. Mackereth "Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin". Open Biology, 13(11):230221. (2023).
Année de publication
2023
Auteurs
S. Thore,
F. Raoelijaona,
V. Talenton,
S. Fribourg,
C. D. Mackereth
Lignes de lumière
rec-number
12999
Référence anonyme
S. Thore,, F. Raoelijaona,, V. Talenton,, S. Fribourg,, C. D. Mackereth "Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin".
Open Biology,
13(11):230221.
(2023).
Type de publication
Date
The cytokinesis regulator RacGAP1 is a Rac1-specific GAP on membranes
Référence
P. Dubois,, Y. Ferrandez,, C. Rey,, C.Pages,, A. Nawrotek,, J. Cherfils "The cytokinesis regulator RacGAP1 is a Rac1-specific GAP on membranes". Protein Science, 35(3):e70488. (2026).
Année de publication
2026
Auteurs
P. Dubois,
Y. Ferrandez,
C. Rey,
C.Pages,
A. Nawrotek,
J. Cherfils
Lignes de lumière
rec-number
12938
Référence anonyme
P. Dubois,, Y. Ferrandez,, C. Rey,, C.Pages,, A. Nawrotek,, J. Cherfils "The cytokinesis regulator RacGAP1 is a Rac1-specific GAP on membranes".
Protein Science,
35(3):e70488.
(2026).
Type de publication
Date
Molecular Basis of c-MET Inhibition by Approved Small Molecule Drugs: A Structural Perspective
Référence
I. C. Russell,, P. Bachurska-Szpala,, L. van Beek,, I. N. Michaelides,, C. Phillips,, A. Snijder,, C. J. Stubbs,, G. W. Collie "Molecular Basis of c-MET Inhibition by Approved Small Molecule Drugs: A Structural Perspective". ACS Medicinal Chemistry Letters, 17(3):590-597. (2026).
Année de publication
2026
Auteurs
I. C. Russell,
P. Bachurska-Szpala,
L. van Beek,
I. N. Michaelides,
C. Phillips,
A. Snijder,
C. J. Stubbs,
G. W. Collie
Lignes de lumière
rec-number
12944
Référence anonyme
I. C. Russell,, P. Bachurska-Szpala,, L. van Beek,, I. N. Michaelides,, C. Phillips,, A. Snijder,, C. J. Stubbs,, G. W. Collie "Molecular Basis of c-MET Inhibition by Approved Small Molecule Drugs: A Structural Perspective".
ACS Medicinal Chemistry Letters,
17(3):590-597.
(2026).
Type de publication
Date
Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe
Référence
A.-S. Banneville,, G. Ferraro,, R. D'Elia,, I. Cornaciu-Hoffmann,, A. Pica,, A. Merlino "Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe". Dalton Transactions, 55():4051-4056. (2026).
Année de publication
2026
Auteurs
A.-S. Banneville,
G. Ferraro,
R. D'Elia,
I. Cornaciu-Hoffmann,
A. Pica,
A. Merlino
Lignes de lumière
rec-number
12961
Référence anonyme
A.-S. Banneville,, G. Ferraro,, R. D'Elia,, I. Cornaciu-Hoffmann,, A. Pica,, A. Merlino "Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe".
Dalton Transactions,
55():4051-4056.
(2026).
Type de publication
Date
Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis
Référence
Z. Edoo,, C. Grosse,, T. Maitre,, R. Frita,, A. Chauffour,, L. Fournier Le Ray,, A. Godmer,, A. Aubry,, M. Bourotte,, R. Antoine,, L. Tawk,, S. Slupek,, V. Trebosc,, B. Schellhorn,, A. Dreneau,, L. Hofmann,, C. Kemmer,, S. Lociuro,, G. E. Dale,, F. Jung,, E. Pérez-Herrán,, A. Mendoza,, M. J. Rebollo López,, S. Ghidelli-Disse,, T. Werner,, L. Ballell,, D. Barros-Aguirre,, V. Mathys,, K. Soetaert,, V. Megalizzi,, R. Wintjens,, M. Gitzinger,, B. Deprez,, N. Veziris,, M. J. Remuiñán,, N. Willand,, M. Pieren,, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis". Nature Communications, online first (07/04/2026)():. (2026).
Année de publication
2026
Auteurs
Z. Edoo,
C. Grosse,
T. Maitre,
R. Frita,
A. Chauffour,
L. Fournier Le Ray,
A. Godmer,
A. Aubry,
M. Bourotte,
R. Antoine,
L. Tawk,
S. Slupek,
V. Trebosc,
B. Schellhorn,
A. Dreneau,
L. Hofmann,
C. Kemmer,
S. Lociuro,
G. E. Dale,
F. Jung,
E. Pérez-Herrán,
A. Mendoza,
M. J. Rebollo López,
S. Ghidelli-Disse,
T. Werner,
L. Ballell,
D. Barros-Aguirre,
V. Mathys,
K. Soetaert,
V. Megalizzi,
R. Wintjens,
M. Gitzinger,
B. Deprez,
N. Veziris,
M. J. Remuiñán,
N. Willand,
M. Pieren,
A. R. Baulard
Lignes de lumière
rec-number
13064
Référence anonyme
Z. Edoo,, C. Grosse,, T. Maitre,, R. Frita,, A. Chauffour,, L. Fournier Le Ray,, A. Godmer,, A. Aubry,, M. Bourotte,, R. Antoine,, L. Tawk,, S. Slupek,, V. Trebosc,, B. Schellhorn,, A. Dreneau,, L. Hofmann,, C. Kemmer,, S. Lociuro,, G. E. Dale,, F. Jung,, E. Pérez-Herrán,, A. Mendoza,, M. J. Rebollo López,, S. Ghidelli-Disse,, T. Werner,, L. Ballell,, D. Barros-Aguirre,, V. Mathys,, K. Soetaert,, V. Megalizzi,, R. Wintjens,, M. Gitzinger,, B. Deprez,, N. Veziris,, M. J. Remuiñán,, N. Willand,, M. Pieren,, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis".
Nature Communications,
online first (07/04/2026)():.
(2026).
Type de publication
Date
25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation
Référence
U. Gómez-Bouzó, , C. Peluso-Iltis, , S. Barreiro, , C. Fernandes, , L. Verlinden, , A. Verstuyf, , F. Borge, , N. Rochel, , G. Gómez, , Y. Fall "25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation". Experimental and Molecular Pathology, 145():105036. (2026).
Année de publication
2026
Auteurs
U. Gómez-Bouzó,
C. Peluso-Iltis,
S. Barreiro,
C. Fernandes,
L. Verlinden,
A. Verstuyf,
F. Borge,
N. Rochel,
G. Gómez,
Y. Fall
Lignes de lumière
rec-number
13072
Référence anonyme
U. Gómez-Bouzó, , C. Peluso-Iltis, , S. Barreiro, , C. Fernandes, , L. Verlinden, , A. Verstuyf, , F. Borge, , N. Rochel, , G. Gómez, , Y. Fall "25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation".
Experimental and Molecular Pathology,
145():105036.
(2026).
Type de publication
Date
The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms
Référence
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms". Nucleic Acids Research, 54(6):. (2026).
Année de publication
2026
Auteurs
Z. Marouf,
C. Tellier-Lebegue,
M. Glousieau,
N. Morellet,
P. Cuniasse,
A. Bourand-Plantefol,
S. Plancqueel,
I. Mahmoudi,
J. Andreani,
P. Legrand,
V. Ropars,
R. Ruedas,
L.-F.Hermouet,
M. Moutiez,
N. Nhiri,
M. Fonvielle,
S. Bressanelli,
T. Katoh,
P. Fernandez Varela,
E. Lescop,
J.-B. Charbonnier,
M. Gondry
Lignes de lumière
rec-number
13068
Référence anonyme
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms".
Nucleic Acids Research,
54(6):.
(2026).
Type de publication
Date
Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation
Référence
S. K. Albanese,, B. E. Hopkins,, A. M. Olland,, A. Fairman,, N. Shaikh,, S. Feng,, M. Thakkar,, A. Verras,, A. Dementiev,, W. G. Walkup 4th,, C. Atsriku,, H. D. Srinivas,, W. Allen,, K. Ashraf,, P. H. Bos,, P. Hsiao,, K.Kroeck,, Z. Liu,, A. Nagarajan,, C. T. Szlenk,, M. Svensson,, Z. Lee Johnson,, K. Kapilashrami,, S. Rubino,, A. Kaplan,, A. M. Levinson* "Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation". Journal of Medicinal Chemistry, 69(8):9521-9536. (2026).
Année de publication
2026
Auteurs
S. K. Albanese,
B. E. Hopkins,
A. M. Olland,
A. Fairman,
N. Shaikh,
S. Feng,
M. Thakkar,
A. Verras,
A. Dementiev,
W. G. Walkup 4th,
C. Atsriku,
H. D. Srinivas,
W. Allen,
K. Ashraf,
P. H. Bos,
P. Hsiao,
K.Kroeck,
Z. Liu,
A. Nagarajan,
C. T. Szlenk,
M. Svensson,
Z. Lee Johnson,
K. Kapilashrami,
S. Rubino,
A. Kaplan,
A. M. Levinson*
Lignes de lumière
rec-number
13099
Référence anonyme
S. K. Albanese,, B. E. Hopkins,, A. M. Olland,, A. Fairman,, N. Shaikh,, S. Feng,, M. Thakkar,, A. Verras,, A. Dementiev,, W. G. Walkup 4th,, C. Atsriku,, H. D. Srinivas,, W. Allen,, K. Ashraf,, P. H. Bos,, P. Hsiao,, K.Kroeck,, Z. Liu,, A. Nagarajan,, C. T. Szlenk,, M. Svensson,, Z. Lee Johnson,, K. Kapilashrami,, S. Rubino,, A. Kaplan,, A. M. Levinson* "Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation".
Journal of Medicinal Chemistry,
69(8):9521-9536.
(2026).
Type de publication
Date