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Modular protein frameworks via supramolecular synthons
Publié le 25/06/2025
... Mockler, N. M., Crowley, P. B. "Modular protein frameworks via supramolecular synthons" Biophysical Reviews., 17: 1057–1080. (2025). ...
Structure-based design of an aromatic helical foldamer–protein interface
Publié le 25/06/2025
... Wang, L., Douat, C., Sigl, J., Reddy, P. S., Fischer, L., Langlois d'Estaintot, B., Liu, Z., Pophristic, V., Yang, Y., Zhang, Y., Ivan Huc, I. "Structure-based design of an aromatic helical foldamer–protein interface" Chemical Science., 16(27): 12385 ...
Status and implementation of the MXCuBE experiment control and ISPyB information system at the P11 macromolecular crystallography beamline at PETRA III (DESY, Hamburg)
Publié le 07/06/2025
... Gruzinov, A., Merkulova, O., Rey-Bakaikoa, V., Pompidor, G., Taberman, H., Chatziefthymiou, S., Grebentsov, A., Meyer, J., Melson, T, Song, J.L., Delsoglio, V., Potturu, S.N., Borges, C., Savko, M., White, T.A., Flewett, S., Schluenzen, F., Rothkirch, A., ...
Un analogue de la vitamine D pour lutter contre le cancer avancé de la prostate
Publié le 03/06/2025
... La vitamine D est connue pour ses activités anticancéreuses, notamment sur la progression du cancer de la prostate, mais son utilisation clinique reste limitée. Des scientifiques de l’Institut de Génétique et de Biologie Moléculaire et ...
Structural insight into the novel Thermus thermophilus SPOUT methyltransferase RlmR catalysing Um2552 formation in the 23S rRNA A-loop: a case of convergent evolution
Publié le 03/06/2025
... Tanouti, Y., Roovers, M., Wolff, P., Lechner, A., Van Elder, D., Feller, A., Soin, R., Gueydan, C., Kruys, V., Droogmans, L., Labar, G. "Structural insight into the novel Thermus thermophilus SPOUT methyltransferase RlmR catalysing Um2552 formation in the ...
Epitope-focused immunogens targeting the hepatitis C virus glycoproteins induce broadly neutralizing antibodies
Publié le 03/06/2025
... Nagarathinam, K., Scheck, A., Labuhn, M., Ströh, L.J., Herold, E., Veselkova, B., Tune, S., Cramer, J.T., Rosset, S., Vollers, S.S., Bankwitz, D., Ballmaier, M., Böning, H., Roth, E., Khera, T., Ahsendorf-Abidi, H.P., Dittrich-Breiholz, O., Obleser, J., ...
Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function
Publié le 27/05/2025
... Dal Maso, T., Sinisgalli, C., Zilio, G., Franzin, E., Tessari, I., Pardon, E., Steyaert, J., Ballet, S., Greggio, E., Versées, W., Plotegher, N. "Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function" Nature ...
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Publié le 21/05/2025
... Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S., Versées, W. "Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity" ACS ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Publié le 25/04/2025
... Seoane, S., Gogoi, P., Zárate-Ruíz, A., Peluso-Iltis, C., Peters, S., Guiberteau, T., Maestro, M.A., Pérez-Fernández, R., Rochel, N., Mouriño, A. "Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring ...