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Imagerie de la maladie d'Alzheimer grâce à trois lignes de lumière de SOLEIL
Publié le 11/09/2023
... La maladie d'Alzheimer - la démence la plus répandue dans le monde - progresse avec le développement dans le cerveau de dépôts de protéines appelés plaques bêta-amyloïdes. Ces plaques peuvent piéger des métaux impliqués dans l'activité du ...
New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex
Publié le 22/08/2023
... Crampon, E., Covernton, E., Vaney, M.C., Dellarole, M., Sommer, S., Sharma, A., Haouz, A., England, P., Lepault, J., Duquerroy, S., Rey, F.A., Barba-Spaeth, G. "New insight into flavivirus maturation from structure/function studies of the yellow fever ...
Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases
Publié le 17/08/2023
... van der Gracht, D., Rowland, R.J., Roig-Zamboni, V., Ferraz, M.J., Louwerse, M., Geurink, P.P., Aerts, J.M.F.G., Sulzenbacher, G., Davies, G.J., Overkleeft, H.S., Artola, M. "Fluorescence polarisation activity-based protein profiling for the ...
Virtual histology of Alzheimer’s Disease: Biometal entrapment within amyloid-plaques allows for detection via X-ray phase-contrast imaging
Publié le 17/08/2023
... Chourrout, M., Sandt, C., Weitkamp, T., Ducic, T., Meyronet, D., Baron, T., Klohs, J., Rama, N., Boutin, H., Singh, S., Olivier, C., Wiart, M., Brun, E., Bohic, S., Chauveau, F. "Virtual histology of Alzheimer’s Disease: Biometal entrapment within amyloid ...
Determining the Kinetics of As4O6·2H2 Formation at High Pressures
Publié le 10/08/2023
... Guńka, P.A., Dziubek,K.F., Capitani, F. "Determining the Kinetics of As4O6·2H2 Formation at High Pressures" Journal of Physical Chemistry C., 127(32): 15871–15875. (2023). ...
Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization
Publié le 01/08/2023
... Jacques, C., Dejean, C., Klose, C., Leccia, E., Bessou-Touya, S., Delarue, A., Duplan, H. "Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization" Skin Pharmacology and Physiology., 36(3): 125–139. (2023). ...
Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA
Publié le 31/07/2023
... Patel, A.K.M., Vilela, P., Shaik, T.B., McEwen, A.G., Hazemann, I., Brillet, K., Ennifar, E., Hamiche, A., Markov, G.V., Laudet, V., Moras, D., Klaholz, B.P., Billas, I.M.L. "Asymmetric dimerization in a transcription factor superfamily is promoted by ...
Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments
Publié le 31/07/2023
... Opuu, V., Nigro, G., Lazennec-Schurdevin, C., Mechulam, Y., Schmitt, E., Simonson, T. "Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments" Protein Science., 32(9): art.n° e4738. (2023). ...
Binding of human Cdc123 to eIF2γ
Publié le 28/07/2023
... Cardenal Peralta, C., Vandroux, P., Neumann-Arnold, L., Panvert, M., Fagart, J., Seufert, W., Mechulam, Y., Schmitt, E. "Binding of human Cdc123 to eIF2γ" Journal of Structural Biology., 215(3): art.n° 108006. (2023). ...
Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
Publié le 21/07/2023
... Maseko, S.B., Brammerloo, Y., Van Molle, I., Sogues, A., Martin, C., Gorgulla, C., Plant, E., Olivet, J., Blavier, J., Ntombela, T., Delvigne, F., Arthanari, H., El Hajj, H., Bazarbachi, A., Van Lint, C., Salehi-Ashtiani, K., Remaut, H., Ballet, S., ...