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N-Acylbenzimidazoles as Selective Acylators of the Catalytic Cystein of the Coronavirus 3CL Protease
Publié le 26/07/2024
... Chaibi, F.Z., Brier, L., Carré, P., Landry, V., Desmarets, L., Tarricone, A., Cantrelle, F.X., Moschidi, D., Herledan, A., Biela, A., Bourgeois, F., Ribes, C., Ikherbane, S., Malessan, M., Dubuisson, J., Belouzard, S., Hanoulle, X., Leroux,, Deprez, B., ...
Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation
Publié le 19/07/2024
... Wallace, M.D., Cuxart, I., Roret, T., Guée, L., Debowski, A.W., Czjzek, M., Rovira, C., Stubbs, K.A., Ficko-Blean, E. "Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation" Angewandte ...
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution
Publié le 16/07/2024
... Ghiglione, B., Rodríguez, M.M., Penzotti, P., Bethel, C.R., Gutkind, G., Bonomo, R.A., Klinke, S., Power, P. "Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution" Antimicrobial ...
A vitamin D-based strategy overcomes chemoresistance in prostate cancer
Publié le 11/07/2024
... Len-Tayon, K., Beraud, C., Fauveau, C., Belorusova, A.Y., Chebaro, Y., Mouriño, A., Massfelder, T., Chauchereau, A., Metzger, D., Rochel, N., Laverny, G. "A vitamin D-based strategy overcomes chemoresistance in prostate cancer" British Journal of ...
Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
Publié le 05/07/2024
... Fernández, I., Saunders, N., Duquerroy, S., Bolland, W.H., Arbabian, A., Baquero, E., Blanc, C., Lafaye, P., Haouz, A., Buchrieser, J., Schwartz, O., Rey, F.A. "Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal ...
Structural and Thermodynamic Insights into Dimerization In-Terfaces of Drosophila Glutathione Transferases
Publié le 27/06/2024
... Schwartz, M., Petiot, N., Chaloyard, J., Senty-Segault, V., Lirussi, F., Senet, P., Nicolai, A., Heydel, J.M., Canon, F., Sonkaria, S., Khare, V., Didierjean, C., Neiers, F. "Structural and Thermodynamic Insights into Dimerization In-Terfaces of ...
Vidéo : Un talisman contre Yazdanduk
Publié le 25/06/2024
... À SOLEIL, les recherches sur le petit talisman mystérieux (voir vidéo « Un talisman qui ne manque pas de caractère(s) ») se poursuivent. Après avoir été virtuellement déroulé par les expériences de tomographie X menées sur la ligne ...
Un talisman contre Yazdanduk
Publié le 25/06/2024
Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain
Publié le 11/06/2024
... Gómez-Bouzó, U., Peluso-Iltis, C., Santalla, H., Quevedo, M.A., Verlinden, L., Verstuyf, A., Fall, Y., Gómez, G., Rochel, N. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain" ...
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction
Publié le 10/06/2024
... Auguin, D., Robert-Paganin, J., Réty, S., Kikuti, C., David, A., Theumer, G., Schmidt, A.W., Knölker, H.J., Houdusse, A. "Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction" Nature Communications. ...