RECHERCHER
Résultats de la recherche ""
Soutenons la lutte contre le cancer avec Blandine ! - Jour 3 du Raid
Publié le 18/10/2018
... Troisième et dernier jour : le binôme des Rubies se classe 17e ! ...
Médicaments anticancéreux innovants : Découverte de nouveaux inhibiteurs de MDM2, protéine impliquée dans la prolifération cellulaire
Publié le 18/10/2018
... L'immortalité des cellules cancéreuses, associée à la perte des mécanismes de contrôle de vie et mort cellulaire, tels que la régulation de l'apoptose (« mort cellulaire programmée »), est un stade récurrent dans l’évolution des ...
Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding Protein
Publié le 17/10/2018
... Zervosen, A., Herman, R., Kerff, F., Herman, A., Bouillez, A., Prati, F., Pratt, R.F., Frère, J.M., Joris, B., Luxen, A., Charlier, P., Sauvage, E. "Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding ...
Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Publié le 17/10/2018
... Woon, E.C.Y., Zervosen, A., Sauvage, E., Simmons, K.J., Živec, M., Inglis, S.R., Fishwick, C.W.G., Gobec, S., Charlier, P., Luxen, A., Schofield, C.J. "Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors" ACS ...
Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.
Publié le 17/10/2018
... Wohlkönig, A., Remaut, H., Moune, M., Tanina, A., Meyer, F., Desroses, M., Steyaert, J., Willand, N., Baulard, A.R., Wintjens, R. "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2 ...
Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate Reductoisomerase with β‐Arylpropyl Analogues of Fosmidomycin
Publié le 17/10/2018
... Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, D., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L. "Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate ...
Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors
Publié le 17/10/2018
... Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465 ...
The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain.
Publié le 17/10/2018
... Rocaboy, M., Herman, R., Sauvage, E., Remaut, H., Moonens, K., Terrak, M., Charlier, P., Kerff, F. "The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain." Molecular Microbiology., ...
First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity
Publié le 17/10/2018
... Pouyez, J., Mayard, A., Vandamme, A.M., Roussel, G., Perpète, E.A., Wouters, J., Housen, I., Michaux, C. "First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its ...
Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH
Publié le 17/10/2018
... Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018). ...