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Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach
Publié le 30/04/2022
... Iannelli, G., Milite, C., Marechal, N., Cura, V., Bonnefond, L., Troffer-Charlier, N., Feoli, A., Rescigno, D., Wang, Y., Cipriano, A., Viviano, M., Bedford, M.T., Cavarelli, J., Castellano, S., Sbardella, G. "Turning Nonselective Inhibitors of Type I ...
L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Publié le 30/04/2022
... Amara, P., Saragaglia, C., Mouesca, J.M., Martin, L., Nicolet, Y. "L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases" Nature Communications., 13: art.n° 2284. (2022). ...
Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin-GPCR Interaction
Publié le 23/04/2022
... Guillien, M., Mouhand, A., Fournet, A., Gontier, A., Navia, A.M., Cordeiro, T.N., Allemand, F., Thureau, A., Banères, J.L., Bernadó, P., Sibille, N. "Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin ...
ComFC mediates transport and handling of single-stranded DNA during natural transformation
Publié le 15/04/2022
... Damke, P.P., Celma, L., Kondekar, S.M., Di Guilmi, A.M., Marsin, S., Dépagne, J., Veaute, X., Legrand, P., Walbott, H., Vercruyssen, J., Guérois, R., Quevillon-Cheruel, S., Radicella, J.P. "ComFC mediates transport and handling of single-stranded DNA ...
Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins
Publié le 05/04/2022
... Zhu, Y., Alvarez, F., Wolff, N., Mechaly, A., Brûlé, S., Neitthoffer, B., Etienne-Manneville, S., Haouz, A., Boëda, B., Caillet-Saguy, C. "Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95 ...
Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix–loop–helix-mediated dimer formation
Publié le 05/04/2022
... Tam, H.K., König, P., Himpich, S., Ngu, N.D., Abele, R., Müller, V., Pos, K.M. "Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix–loop–helix-mediated dimer formation" PNAS., 119(14): art.n° e2107994119. (2022). ...
SAXS Investigation of Core–Shell Microgels with High Scattering Contrast Cores: Access to Structure Factor and Volume Fraction
Publié le 05/04/2022
... Hildebrandt, M., Lazarev, S., Pérez, J., Vartanyants, I.A., Meijer, J.M., Karg, M. "SAXS Investigation of Core–Shell Microgels with High Scattering Contrast Cores: Access to Structure Factor and Volume Fraction" Macromolecules., 55(7): 2959-2969. (2022). ...
Structural dynamics of the C-terminal X domain of Nipah and Hendra viruses controls the attachment to the C-terminal tail of the nucleocapsid protein
Publié le 01/04/2022
... Bourhis, J.M., Yabukarski, F., Communie, G., Schneider, R., Volchkova, V.A., Frénéat, M., Gérard, F., Ducournau, C., Mas, C., Tarbourie, N., Ringkjøbing Jensen, M., Volchkov, V.E., Blackledge, M., Jamin, M. "Structural dynamics of the C-terminal X domain ...
A large disordered region confers a wide spanning volume to vertebrate Suppressor of Fused as shown in a trans-species solution study
Publié le 31/03/2022
... Makamte, S., Thureau, A., Jabrani, A., Paquelin, A., Plessis, A., Sanial, M., Rudenko, O., Oteri, F., Baaden, M., Biou, V. "A large disordered region confers a wide spanning volume to vertebrate Suppressor of Fused as shown in a trans-species solution ...
CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation
Publié le 31/03/2022
... Carrasco, K., Montersino, C., Derviaux, C., Saez-Ayala, M., Hoffer, L., Restouin, A., Castellano, R., Casassa, J., Roche, P., Pasquier, E., Combes, S., Morelli, X., Collette, Y., Betzi, S. "CRCM5484: A BET-BDII Selective Compound with Differential Anti ...