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Résultats de la recherche ""
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors
Publié le 22/02/2025
... Mfuh, A.M., Boerth, J.A., Bommakanti, G., Chan, C., Chinn, A.J., Code, E., Fricke, P.J., Giblin, K.A., Gohlke, A., Hansel, C., Hariparsad, N., Hughes, S.J., Jin, M., Kantae, V., Kavanagh, S.L., Lamb, M.L., Lane, J., Moore, R., Puri, T., Quinn, T.R., Reddy ...
Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Publié le 22/02/2025
... Cellupica, E., Gaiassi, A., Rocchio, I., Rovelli, G., Pomarico, R., Sandrone, G., Caprini, G., Cordella, P., Cukier, C., Fossati, G., Marchini, M., Bebel, A., Airoldi, C., Palmioli, A., Stevenazzi, A., Steinkuhler, C., Vergani, B. "Mechanistic and ...
Structural insights into tecovirimat antiviral activity and poxvirus resistance
Publié le 14/02/2025
... Vernuccio, R., Martínez León, A., Poojari, C.S., Buchrieser, J., Selverian, C.N., Jaleta, Y., Meola, A., Guivel-Benhassine, F., Porrot, F., Haouz, A., Chevreuil, M., Raynal, B., Mercer, J., Simon-Loriere, S., Chandran, K., Schwartz, O., Hub, J.S., ...
Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair
Publié le 11/02/2025
... Claustre, A., Malige, M., Macheton, M., Combaret, L., Lefai, E., Fafournoux, P., Taillandier, D., Henri, J., Polge, C. "Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair" ...
Skin, scales, and cells in a Jurassic plesiosaur
Publié le 08/02/2025
... Marx, M., Sjövall, P., Kear, B.P., Jarenmark, M., Eriksson, M.E., Sachs, S., Nilkens, K., Op De Beeck, M., Lindgren, J. "Skin, scales, and cells in a Jurassic plesiosaur" Current Biology., 35(5): 1113-1120. (2025). ...
RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases
Publié le 07/02/2025
... Coste, F., Mishra, A., Chapuis, C., Mance, L., Pukało,Z., Bigot,N., Goffinont, S., Gaudon, V., Garnier, N., Talhaoui, I., Castaing, B., Huet, S., Suskiewicz, M.J. "RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases" FEBS ...
Mid-infrared detection and characterization of refractory inclusions in CM and CO chondrites: A non-destructive approach for returned space samples
Publié le 05/02/2025
... Charlier, J., Aléon-Toppani, A., Brunetto, R., Aléon, J., Borondics, F. "Mid-infrared detection and characterization of refractory inclusions in CM and CO chondrites: A non-destructive approach for returned space samples" Meteoritics & Planetary Science., ...
Antibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivo
Publié le 01/02/2025
... Dejoux, A., Zhu, Q., Woolfe, A., Godon, O., Ellouze, S., Mottet, G., Castrillon, C., Gillis, C., Pecalvel, C., Ganneau, C., Iannascoli, B.., Lemoine, F., Saul, F., England, P., Reber, L.L., Gouel-Chéron, A., de Chaisemartin, L., Haouz, A., Millot, G.A., ...