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Probing Macromolecular Interactions by Loss of Solvent Content in Protein Crystals: Application to the Amyloid-β Peptide Binding to Transthyretin
Publié le 23/05/2025
... Costa-Rodrigues, D., Leite, J.P., Gales, L. "Probing Macromolecular Interactions by Loss of Solvent Content in Protein Crystals: Application to the Amyloid-β Peptide Binding to Transthyretin" Crystal Growth & Design., 25(10): 3511-3517 . (2025). ...
Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists
Publié le 23/05/2025
... Amaudrut, J., Argiriadi, M.A., Barth, M., Breinlinger, E.C., Bressac, D., Broqua, P., Calderwood, D.J., Chatar, M., Cusack, K.P., Gauld, S.B., Jacquet, S., Kamath, R.V., Kort, M.E., Lepais, V., Luccarini, J.M., Masson, P., Montalbetti, C., Mounier, L., ...
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Publié le 23/05/2025
... Tron, A.E., Belmonte, M.A., Adam, A., Aquila, B.M., Boise, L.H., Chiarparin, E., Cidado, J., Embrey, K.J., Eric Gangl, E., Gibbons, F.D., Gregory, G.P., Hargreaves, D., Hendricks, J.A., Johannes, J.W., Johnstone, R.W., Kazmirski, S.L., Kettle, J.G., Lamb, ...
Platinum nanoparticle stability promotion in PEMFC via metal oxide addition: A comparative study between GDE and MEA
Publié le 21/05/2025
... Parnigotto, M., Mazzucato, M., Zitolo, A., Cotte, S., Durante, C. "Platinum nanoparticle stability promotion in PEMFC via metal oxide addition: A comparative study between GDE and MEA" Chemical Engineering Journal., 515: art.n° 163521. (2025). ...
Enhancing CoFe Catalysts with V2CTX MXene-Derived Materials for Anion Exchange Membrane Electrolyzers
Publié le 21/05/2025
... Kaplan, C., Dharmaraj, K., Schultz, T., Qin, L., Chen, N., Douglas-Henry, D.A., Schmiedecke, B., Buldu-Akturk, M., Zuber, A., Dorbandt, I., Reinhardt, M., Rodriguez-Ayllon, Y., Lu, Y., Nicolosi, V., Koch, N., Rosen, J., Browne, M.P. "Enhancing CoFe ...
Structural Dynamic Evolution of Pt Nanoclusters in Ultra-Low-Temperature Methane Combustion with Nitrous Oxide
Publié le 29/04/2025
... Hong, R., Wu, Y., Su, Y., Stavitski, E., Wang, H., Wu, Z., Wu, X., Weng, X. "Structural Dynamic Evolution of Pt Nanoclusters in Ultra-Low-Temperature Methane Combustion with Nitrous Oxide" ACS Applied Materials & Interfaces., 17(18): 26523–26533. (2025). ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Mechanism of read-through enhancement by aminoglycosides and mefloquine
Publié le 25/04/2025
... Kolosova, O., Zgadzay, Y., Stetsenko, A., Sukhinina, A.P., Atamas, A., Validov, S., Rogachev, A., Usachev, K., Jenner, L., Dmitriev, S.E., Yusupova, G., Guskov, A., Yusupov, M. "Mechanism of read-through enhancement by aminoglycosides and mefloquine" PNAS ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity
Publié le 15/04/2025
... Cornelius, P., Mayes, B.A., Petersen, J.S., Turnquist, D.J., Dufour, P.J., Dannenberg, A.J., Shanahan, J.M., Carver, B.J. "Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and ...