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The reaction mechanism of metallo-β-Lactamases is tuned by the conformation of an active site mobile loop
Publié le 31/10/2018
... Palacios, A.R., Mojica, M.F., Giannini, E., Taracila, M.A., Bethel, C.R., Alzari, P.M., Otero, L.H., Klinke, S., Llarrull, L.I., Bonomo, R.A., Vila, A.J. "The reaction mechanism of metallo-β-Lactamases is tuned by the conformation of an active site mobile ...
Structure and genome ejection mechanism of Podoviridae phage P68 infecting Staphylococcus aureus
Publié le 31/10/2018
... Hrebik, D., Stverakova, D., Skubnik, K., Fuzik, T., Pantucek, R., Plevka, P. "Structure and genome ejection mechanism of Podoviridae phage P68 infecting Staphylococcus aureus". BioRxiv., preprint: (2018). ...
Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography
Publié le 31/10/2018
... de Aguiar Amaral, P., Autheman, D., Dias de Melo, G., Gouault, N., Cupif, J.F., Goyard, S., Dutra, P., Coatnoan, N., Cosson, A., Monet, D., Saul, F., Haouz, A., Uriac, P., Blondel, A., Minoprio, P. "Designed mono- and di-covalent inhibitors trap modeled ...
Genetic and Biochemical Characterization of OXA-535, a Distantly Related OXA-48-Like β-Lactamase
Publié le 31/10/2018
... Dabos, L., Jousset, A.B., Bonnin, R.A., Fortineau, N., Zavala, A., Retailleau, P., Iorga, B.I., Naas, T. "Genetic and Biochemical Characterization of OXA-535, a Distantly Related OXA-48-Like β-Lactamase" Antimicrobial Agents Chemotherapy., 62(10): art.n° ...
The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite
Publié le 31/10/2018
... Bernhardsgrütter, I., Vögeli, B., Wagner, T., Peter, D.M., Socorro Cortina, N., Bange, G., Engilberge, S., Girard, E., Riobé, F., Maury, O., Shima, S., Zarzycki, J., Erb, T.J. "The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic ...
The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase
Publié le 30/10/2018
... Castro-Rodrigues, A.F., Zhao, Y., Fonseca, F., Gabant, G., Cadene, M., Robertson, G.A., Morais-Cabral, J.H. "The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of ...
Dissociation of the dimer of the intrinsically disordered domain of RNase Y upon antibody binding
Publié le 29/10/2018
... Hardouin, P., Velours, C., Bou-Nader, C., Assrir, N., Laalami, S., Putzer, H., Durand, D., Golinelli-Pimpaneau, B. "Dissociation of the dimer of the intrinsically disordered domain of RNase Y upon antibody binding" Biophysical Journal., 115(11): 2102 ...
Un solide nanoporeux pour une réfrigération plus efficace
Publié le 26/10/2018
... La récupération de chaleur (énergie solaire, pompes à chaleur, climatisation, réfrigération…) s’avère un enjeu technologique d’importance croissante à l’heure de la prise de conscience de l’importance du développement durable et de la ...
A robust large-pore zirconium carboxylate metal–organic framework for energy-efficient water-sorption-driven refrigeration
Publié le 24/10/2018
... Wang, S., Lee, J.S., Wahiduzzaman, M., Park, J., Muschi, M., Martineau-Corcos, C., Tissot, A., Cho, K.H., Marrot, J., Shepard, W., Maurin, G., Chang, J.S., Serre, C. "A robust large-pore zirconium carboxylate metal–organic framework for energy-efficient ...
Characterization of histone deacetylase 8 (HDAC8) selective inhibition reveals specific active site structural and functional determinants
Publié le 24/10/2018
... Marek, M., Shaik, T.B., Heimburg, T., Chakrabarti, A., Lancelot, J., Ramos Morales, E., Da Veiga, C., Kalinin, D.V., Melesina, J., Robaa, D., Schmidtkunz, K., Suzuki, T., Holl, R., Ennifar, E., Pierce, R., Jung, M., Sippl, W., Romier, C. "Characterization ...