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Résultats de la recherche ""
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
Publié le 25/03/2025
... Hillen, H., Candi, A., Vanderhoydonck, B., Kowalczyk, W., Sansores-Garcia, L., Kesikiadou, E.C., Van Huffel, L., Spiessens, L., Nijs, M., Soons, E., Haeck, W., Klaassen, H., Smets, W., Spieser, S.A., Marchand, A., Chaltin, P., Ciesielski, F., Debaene, F., ...
Holdup Multiplex Assay for High-Throughput Measurement of Protein–Ligand Affinity Constants Using a Mass Spectrometry Readout
Publié le 25/03/2025
... Delalande, F., Østergaard, S., Gogl, G., Cousido-Siah, A., McEwen, A., Men, Y., Salimova, F., Rohrbacher, A., Kostmann, C., Nominé, Y., Vincentelli, R., Eberling, P., Carapito, C., Travé, G., Monsellier, E. "Holdup Multiplex Assay for High-Throughput ...
Angle dependance Spin Crossover properties in polymorphic Iron(II) complexes based on pyridine-triazole derivatives
Publié le 20/03/2025
... Cuza, E., Delsuc, N., Marrot, J., Shepard, W.E., Policar, C., Serre, C., Tissot, A. "Angle dependance Spin Crossover properties in polymorphic Iron(II) complexes based on pyridine-triazole derivatives" Dalton Transactions., 54(15): 6274-6280. (2025). ...
Metal-organic chelator frameworks for arsenic-based cancer treatment
Publié le 18/03/2025
... Celaya-Azcoaga, L., Crespi, A., Shepard, W., Quezada, R., Peralta Ramos, M.L., Cavallo, M., Irastorza Epelde, I., Garcia Garcia, H., Barandika, G., Bonino, F., García, A., Copello, G.J., Castillo, O., Silván, U., Fernández de Luis, R. "Metal-organic ...
Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus
Publié le 13/03/2025
... Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., Kirschning, A. "Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus" Nature Communications., 16: ...
Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel
Publié le 13/03/2025
... Karlsson, E., Andén, O., Fan, C., Fourati, Z., Haouz, A., Zhuang, Y., Howard, R.J., Delarue, M., Lindahl, E. "Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel" British Journal of Pharmacology., 182(12): 2790-2802. ...
Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands
Publié le 11/03/2025
... Sieskind, R., Missoury, S., Madru, C., Commenge, I., Niogret, G., Hollenstein, M., Rondelez, Y., Sauguet, L., Haouz, A., Legrand, P., Delarue, M. "Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two ...
Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans DsijT
Publié le 11/03/2025
... Chevenier, A., Fanuel, M., Sokolova, E., Latorre, D.M., Jouanneau, D., Jeudy, A., Préchoux, A., Zühlke, M.K., Bartel, J., Becher, D., Czjzek, M., Ropartz, D., Michel, G., Ficko-Blean, E. "Structure, function and catalytic mechanism of the carrageenan ...
Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity
Publié le 28/02/2025
... Neuville, M., Bourgeais, M., Buratto, J., Saragaglia, C., Li, B., Galeano-Otero, I., Mauran, L., Varajao, L., Goudreau, S.R., Kauffmann, B., Thinon, E., Pasco, M., Khatib, A.M., Guichard, G. "Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C ...
Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State
Publié le 25/02/2025
... Pecqueur, L., Lombard, M., Hamdane, D. "Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State" Biomolecules., 15(3): art.n° 318. (2025). ...