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Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Publié le 21/05/2025
... Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S., Versées, W. "Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity" ACS ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Publié le 25/04/2025
... Seoane, S., Gogoi, P., Zárate-Ruíz, A., Peluso-Iltis, C., Peters, S., Guiberteau, T., Maestro, M.A., Pérez-Fernández, R., Rochel, N., Mouriño, A. "Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring ...
Mechanism of read-through enhancement by aminoglycosides and mefloquine
Publié le 25/04/2025
... Kolosova, O., Zgadzay, Y., Stetsenko, A., Sukhinina, A.P., Atamas, A., Validov, S., Rogachev, A., Usachev, K., Jenner, L., Dmitriev, S.E., Yusupova, G., Guskov, A., Yusupov, M. "Mechanism of read-through enhancement by aminoglycosides and mefloquine" PNAS ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity
Publié le 15/04/2025
... Cornelius, P., Mayes, B.A., Petersen, J.S., Turnquist, D.J., Dufour, P.J., Dannenberg, A.J., Shanahan, J.M., Carver, B.J. "Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and ...
N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle
Publié le 11/04/2025
... Ifeagwu, M.C., Guo, L., Mockler, N.M., Dong, M., Li, C., Crowley, P.B. "N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle" Crystal Growth & Design., 25(13): 4661-4665. (2025). ...
Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons.
Publié le 11/04/2025
... Ganatra, P., Wang, D.F., Ganatra, V., Dang, V.T., Nguyen, A.I. "Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons." Journal of the American Chemical Society., 146(32): 22236–22246. (2024). ...
How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation
Publié le 11/04/2025
... Contaldo, U., Santucci, P., Vergnes, A., Leone, P., Becam, J., Biaso, F., Ilbert, M., Ezraty, B., Lojou, E., Mazurenko, I. "How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation" JACS Au., 5(4): 1833-1844. (2025). ...
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Publié le 10/04/2025
... Shields, J.D., Aquila, B.M., Emmons, D., Finlay, M.R.V., Gangl, E.T., Gu, C., Mlynarski, S.N., Petersen, J., Pop-Damkov, P., Li Sha, L., Simpson, I., Tavakoli, S., Tentarelli, S., Wang, H., Ye, Q., Zheng, X.L. "Design and Synthesis of Acyclic Boronic Acid ...