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Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity
Publié le 01/08/2020
... Fieulaine, S., Witte, M.D., Theile, C.S., Ploegh, H.L., Jupin, I., Bressanelli, G. "Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity" Journal of Biological Chemistry., 295(40): 13769-13783. (2020). ...
Dissecting the structural and chemical determinants of the 'open-to-closed' motion in the mannosyltransferase PimA from mycobacteria
Publié le 30/07/2020
... Rodrigo-Unzueta, A., Ghirardello, M., Urresti, S., Delso, I., Giganti, D., Anso, I., Trastoy, B., Comino, N., Tersa, M., D'Angelo, C., Cifuente, J.O., Marina, A., Liebau, J., Mäler, L., Chenal, A., Albesa-Jove, D., Merino, P., Guerin, M.E. "Dissecting the ...
Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59
Publié le 30/07/2020
... Pellizza, L., López, J.L., Vázquez, S., Sycz, G., Guimarães, B.G., Rinaldi, J., Goldbaum, F.A., Aran, M., Mac Cormack, W.P., Klinke, S. "Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic ...
Monoaryl derivatives as Transthyretin fibril formation inhibitors: design, synthesis, biological evaluation and structural analysis
Publié le 30/07/2020
... Ciccone, L., Nencetti, S., Tonali, N., Fruchart-Gaillard, C.,, Shepard, W., Nuti, E., Camodeca, C., Rossello, A., Orlandini, E. "Monoaryl derivatives as Transthyretin fibril formation inhibitors: design, synthesis, biological evaluation and structural ...
Les vidéos doublées en LSF, un signe d’accessibilité
Publié le 29/07/2020
... Une troisième vidéo sous-titrée en français (VFSTF) et doublée en langue des signes française (LSF) est disponible. ...
An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity
Publié le 29/07/2020
... Debruycker, V., Hutchin, A., Masureel, M., Ficici, E., Martens, C., Legrand, P., Stein, R.A., Mchaourab, H.S., Faraldo-Gómez, J.D., Remaut, H., Govaerts, C. "An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity" ...
Timeless couples G‐quadruplex detection with processing by DDX 11 helicase during DNA replication
Publié le 28/07/2020
... Lerner, L.K., Holzer, S., Kilkenny, M.L., Šviković, S., Murat, P., Schiavone, D., Eldridge, C.B., Bittleston, A., Maman, J.D., Branzei, D., Stott, K., Pellegrini, L., Sale, J.E. "Timeless couples G‐quadruplex detection with processing by DDX 11 helicase ...
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
Publié le 28/07/2020
... Lara, J., Diacovich, L., Trajtenberg, F., Larrieux, N., Malchiodi, E.L., Fernández, M.M., Gago, G., Gramajo, H., Buschiazzo, A. "Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine" Nature ...
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents
Publié le 25/07/2020
... Jian, Y., Merceron, R., De Munck, S., Forbes, H.E., Hulpia, F., Risseeuw, M.D.P., Van Hecke, K., Savvides, S.N., Munier-Lehmann, H., Boshoff, H.I.M., Van Calenbergh, S. "Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) ...
Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase
Publié le 21/07/2020
... Gadakh, B., Vondenhoff, G., Pang, L., Nautiyal, M., De Graef, S., Strelkov, S.V., Weeks, S.D., Van Aerschot, A. "Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA ...