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Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein
Publié le 22/01/2022
... Fuchsbauer, O., Silva, I.L., Cascales, E., Roussel, A., Leone, P. "Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein" Journal of Biological Chemistry., 298(3): art.n° 101618. (2022). ...
Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach
Publié le 21/01/2022
... Charoensutthivarakul, S., Thomas, S.E., Curran, A., Brown, K.P., Belardinelli, J.M., Whitehouse, A.J., Acebrón-García-de-Eulate, M., Sangan, J., Gramani, S.G., Jackson, M., Mendes, V., Floto, R.A., Blundell, T.L., Coyne, A.G., Abell, A. "Development of ...
Atomic structure of Lanreotide nanotubes revealed by cryo-EM
Publié le 20/01/2022
... Pieri, L., Wang, F., Arteni, A.A., Vos, M., Winter, J.M., Le Du, M.H., Artzner, F., Gobeaux, F., Legrand, P., Boulard, Y., Bressanelli, S., Egelman, E.H., Paternostre, M. "Atomic structure of Lanreotide nanotubes revealed by cryo-EM" PNAS., 119(4): art.n ...
Implementation of wedged-serial protein crystallography at PROXIMA-1
Publié le 19/01/2022
... Chaussavoine, I., Isabet, T., Lerner, L.K., Montaville, P., Vasireddi, R., Chavas, L.M.G. "Implementation of wedged-serial protein crystallography at PROXIMA-1" Journal of Synchrotron Radiation., 29(2): 439-446. (2022). ...
Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding
Publié le 14/01/2022
... Gajdos, L., Blakeley, M.P., Haertlein, M., Forsyth, V.T., Devos, J.M., Imberty, A. "Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding" Nature Communications., 13: art.n° 194. (2022). ...
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
Publié le 14/01/2022
... Danis, C., Dupré, E., Zejneli, O., Caillierez, R., Arrial, A., Bégard, S., Mortelecque, J., Eddarkaoui, S., Loyens, A., Cantrelle, F.X., Hanoulle, X., Rain, J.C., Colin, M., Buée, L., Landrieu, I. "Inhibition of Tau seeding by targeting Tau nucleation ...
Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states
Publié le 13/01/2022
... Takahashi, D.T., Gadelle, D., Agama, K., Kiselev, E., hang, H., Yab, E., Petrella, S., Forterre, P., Pommier, Y., Mayer, C. "Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states" Nature Communications., 13: art.n° 59. ...
B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner
Publié le 13/01/2022
... Stein, A., Hilken née Thomopoulou, P., Frias, C.., Hopff, S.M., Varela, P., Wilke, N., Mariappan, A., Neudörfl, J.M., Fedorov, A.Y., Gopalakrishnan, J., Gigant, B., Prokop, A., Schmalz, H.G. "B-nor-methylene Colchicinoid PT-100 Selectively Induces ...
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps
Publié le 13/01/2022
... Plé, C., Tam, H.K., Vieira Da Cruz, A., Compagne, N., Jiménez-Castellanos, J.C., Müller, R.T., Pradel, E., Foong, W.E., Malloci, G., Ballée, A., Kirchner, M.A., Moshfegh, P., Herledan, A., Herrmann, A., Deprez, B., Willand, N., Vargiu, A.V., Pos, K.M., ...
Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives
Publié le 13/01/2022
... Kostyuk, A.I., Tossounian, M.A., Panova, A.S., Thauvin, M., Raevskii, R.I., Ezeriņa,D., Wahni,K., Van Molle,I., Sergeeva,A.D., Vertommen,D., Gorokhovatsky,A.Y., Baranov,M.S., Vriz,S., Messens,J., Bilan, D.S., Belousov, V.V. "Hypocrates is a genetically ...