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Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity
Publié le 16/02/2023
... Morais, K.L.P., Ciccone, L., Stura, E., Alvarez-Flores, M.P., Mourier, G., Vanden Driessche, M., Sciani, J.M., Iqbal, A., Kalil, S.P., Pereira, G.J., Marques-Porto, R., Cunegundes, P., Servent, J.D., Chudzinski-Tavassi, A.M. "Structural and functional ...
Biochemical ans structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize
Publié le 16/02/2023
... Bělíček,J., Ľuptáková, E., Kopečný, D., Frömmel, J., Vigouroux, A., Zeljković,S.C., Jagic,F., Briozzo,P., Kopečný, D.J., Tarkowski, P., Nisler, J., De Diego, N., Moréra, S., Kopečná, M. "Biochemical ans structural basis of polyamine, lysine and ornithine ...
The LH–DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders
Publié le 07/02/2023
... Cargemel, C., Marsin, S., Noiray, M., Legrand, P., Bounoua, H., Li de la Sierra-Gallay, I., Walbott, H., Quevillon-Cheruel, S. "The LH–DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders" Acta ...
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses
Publié le 07/02/2023
... Brier, L., Hassan, H., Hanoulle, X., Landry, V., Moschidi, D., Desmarets, L., Rouillé, Y., Dumont, J., Herledan, A., Warenghem, S., Piveteau, C., Carré, P., Ikherbane, S., Cantrelle, F.X., Dupré, E., Dubuisson, J., Belouzard, S., Leroux, F., Deprez, B., ...
Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists
Publié le 07/02/2023
... Mousavifar, L., Sarshar, M., Bridot, C., Scribano, D., Ambrosi, C., Palamara, A.T., Vergoten, G., Roubinet, B., Landemarre, L., Bouckaert, J., Roy, R. "Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists" Pharmaceutics., ...
A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea
Publié le 03/02/2023
... Daugeron, M.C., Missoury, S., Da Cunha, V., Lazar, N., Collinet, B., van Tilbeurgh, H., Basta, T. "A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea" Nature Communications., 14: art.n° 526. (2023). ...
Structural and Biochemical Features of OXA-517: a Carbapenem and Expanded-Spectrum Cephalosporin Hydrolyzing OXA-48 Variant
Publié le 24/01/2023
... Dabos, L., Raczynska, J.E., Bogaerts, P., Zavala, A., Girlich, D., Bonnin, R.A., Dortet, L., Peyrat, A., Retailleau, P., Iorga, B.I., Jaskólski, M., Glupczynski, Y., Naas, T. "Structural and Biochemical Features of OXA-517: a Carbapenem and Expanded ...
Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales
Publié le 20/01/2023
... Jespersen, M., Pierik, A.J., Wagner, T. "Structures of the sulfite detoxifying F420-dependent enzyme from Methanococcales" Nature Chemical Biology., 19(6): 695–702. (2023). ...
Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies
Publié le 20/01/2023
... Panek, D., Pasieka, A., Latacz, G., Zaręba,P., Szczęch,M., Godyń,J., Chantegreil, F., Nachon,F., Brazzolotto,X., Skrzypczak-Wiercioch,A., Walczak, M., Smolik,M., Sałat,K., Höfner, G., Wanner, K., Więckowska,A., Malawska, B. "Discovery of new, highly ...
The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors
Publié le 20/01/2023
... Ainelo, A., Caballero-Montes, J., Bulvas, O., Ernits, K., Coppieters ‘t Wallant, K., Takada, H., Craig, S.Z., Mazzucchelli, G., Zedek, S., Pichová, I., Atkinson, G.C., Talavera, A., Martens, C., Hauryliuk, V., Garcia-Pino, A. "The structure of DarB in ...