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The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA
Publié le 05/11/2025
... Leusmann, S., Siebs, E., Kuhaudomlarp, S., Varrot, A., Imberty, A., Kuhn, B., Lerner, C., Grether, U., Titz, A. "The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA" Angewandte ...
New promising transthyretin stabilizers for cardiac amyloidosis treatment
Publié le 04/11/2025
... Ciccone, L., Camodeca, C., Fruchart-Gaillard, C., Thaï, R., Tonali, N., Basta, G., Del Turco, S., Russo, L., Noiray, M., Sirigu, S., Shepard, W., Barlettani, L., Mazzocchi, F., Orlandini, E., Nencetti, S. "New promising transthyretin stabilizers for ...
Carbon-monoxide-driven bioethanol production operates through a tungsten-dependent catalyst
Publié le 30/10/2025
... Lemaire, O.N., Belhamri, M., Shevchenko, A., Wagner, T. "Carbon-monoxide-driven bioethanol production operates through a tungsten-dependent catalyst" Nature Chemical Biology., 22(1): 28–36. (2026). ...
A new chemotype that opens the S2* pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2.
Publié le 30/10/2025
... Mourot, L., Chaibi, F.Z., Bou-Karroum, N., Carré, P., Abengozar Munoz, A., Landry, V., Tarricone, A., Biela, A., Piveteau, C., Novikov, G., Dupré, E., Dubuisson, J., Belouzard, S., Leroux, F., Deprez, B., Hanoulle, X., Charton, J. "A new chemotype that ...
Accelerating Synchrotron MX Beamlines: Automated Sample Centering with Machine Learning and Bluesky Orchestration
Publié le 28/10/2025
... Aragao, D., Savko, M., Oram, D., Smith, K., Shepard, W., Flaig, R. "Accelerating Synchrotron MX Beamlines: Automated Sample Centering with Machine Learning and Bluesky Orchestration" Structural Dynamics., 12(5): art.n° A47. (2025). ...
Cryo-EM structural analyses reveal plant-specific adaptations of the CDC48 unfoldase
Publié le 27/10/2025
... Huntington, B., Sandholu, A., Wang, J., Zhang, J., Zhao, L., Qureshi, B., Hameed, U.F.S., Arold, S.T. "Cryo-EM structural analyses reveal plant-specific adaptations of the CDC48 unfoldase".
Plant Communications,
7(1):art.n° ...
Structural and Spectroscopic Insights into Catalytic Intermediates of a [NiFe]-hydrogenase from Group 3
Publié le 15/10/2025
... Jespersen, M., Lorent, C., Lemaire, O.N., Zebger, I., Wagner, T. "Structural and Spectroscopic Insights into Catalytic Intermediates of a [NiFe]-hydrogenase from Group 3" ChemBioChem., 26(21): art.n° e202500692. (2025). ...
Polyoxometalate-Directed Assembly of Robust Coordination Cages: Overcoming Kinetic Inertness and Conformational Mismatch
Publié le 13/10/2025
... Liu, C.L., Jia, X., Ham, R., Ren, C., Van Meervelt, L., Reek, J.N.H., Parac-Vogt, T.N. "Polyoxometalate-Directed Assembly of Robust Coordination Cages: Overcoming Kinetic Inertness and Conformational Mismatch" Angewandte Chemie International Edition., 64 ...
Dipeptidase 1 is a functional receptor for a porcine coronavirus
Publié le 13/10/2025
... Dufloo, J., Fernández, I., Arbabian, A., Haouz, A., Temperton, N., Gimenez-Lirola, L.G., Rey, F.A., Sanjuán, R. "Dipeptidase 1 is a functional receptor for a porcine coronavirus" Nature Microbiology., 10(11): 2981–2996. (2025). ...
Une nouvelle cible pour traiter le virus mpox (variole du singe) et d’autres infections poxvirales
Publié le 10/09/2025
... Le mpox est une maladie infectieuse transmise par contact, pouvant être mortelle ou laisser des séquelles importantes. Des chercheurs de l’Institut Pasteur ont identifié et caractérisé une nouvelle cible pour développer des thérapies capables ...