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Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus
Publié le 13/03/2025
... Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., Kirschning, A. "Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus" Nature Communications., 16: ...
Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel
Publié le 13/03/2025
... Karlsson, E., Andén, O., Fan, C., Fourati, Z., Haouz, A., Zhuang, Y., Howard, R.J., Delarue, M., Lindahl, E. "Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel" British Journal of Pharmacology., 182(12): 2790-2802. ...
Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands
Publié le 11/03/2025
... Sieskind, R., Missoury, S., Madru, C., Commenge, I., Niogret, G., Hollenstein, M., Rondelez, Y., Sauguet, L., Haouz, A., Legrand, P., Delarue, M. "Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two ...
Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans DsijT
Publié le 11/03/2025
... Chevenier, A., Fanuel, M., Sokolova, E., Latorre, D.M., Jouanneau, D., Jeudy, A., Préchoux, A., Zühlke, M.K., Bartel, J., Becher, D., Czjzek, M., Ropartz, D., Michel, G., Ficko-Blean, E. "Structure, function and catalytic mechanism of the carrageenan ...
Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity
Publié le 28/02/2025
... Neuville, M., Bourgeais, M., Buratto, J., Saragaglia, C., Li, B., Galeano-Otero, I., Mauran, L., Varajao, L., Goudreau, S.R., Kauffmann, B., Thinon, E., Pasco, M., Khatib, A.M., Guichard, G. "Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C ...
Modulating the surface chemistry of gold nanoparticles produced via laser ablation in liquids by favored oxidative processes in the presence of Br anions
Publié le 28/02/2025
... Lévy, A., Blanchet, V., Bozek, J.D., Cabailh, G., De Anda Villa, M., Gaudin, J., Guilet, S., Lamour, E., Macé, S., Milosavljević, A.R., Prigent, C., Robert, E., Steydli, S., Trassinelli, M., Vernhet, D., Amans, D. "Modulating the surface chemistry of gold ...
Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State
Publié le 25/02/2025
... Pecqueur, L., Lombard, M., Hamdane, D. "Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State" Biomolecules., 15(3): art.n° 318. (2025). ...
Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis
Publié le 22/02/2025
... Schulze, M.S.E.D., Scholz, D., Jnoff, E., Hall, A., Melin, J., Sands, Z.A., Rodriguez, E., Andre, V.M. "Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis" ChemMedChem., 19(7): art.n° e202300548. (2024). ...
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...