RECHERCHER
Résultats de la recherche ""
Targeting undruggable carbohydrate recognition sites through focused fragment library design
Publié le 24/05/2022
... Shanina, E., Kuhaudomlarp, S., Siebs, E., Fuchsberger, F.F., Denis, M., Gomes, P.S.F.C., Mads H., Clausen, M.H., Seeberger, P.H., Rognan, D., Titz, A., Imberty, A., Rademacher, C. "Targeting undruggable carbohydrate recognition sites through focused ...
Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase
Publié le 19/05/2022
... Meynier, V., Iannazzo, L., Catala, M., Oerum, S., Braud, E., Atdjian, C., Barraud, P., Fonvielle, M., Tisné, C., Ethève-Quelquejeu, M. "Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase" ...
Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development
Publié le 18/05/2022
... Sharma, M., Mutharasappan, N., Manickam, Y., Harlos, K., Melillo, B., Comer, E., Tabassum, H., Parvez, S., Schreiber, S.L., Sharma, A. "Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug ...
Immunité - La diffraction X relève des interactions entre protéines au cœur de la défense contre les pathogènes
Publié le 17/05/2022
... En permanence, le système immunitaire identifie et détruit bactéries pathogènes, virus et autres facteurs d’infection. Le système du complément est l’un de ses composants, constitué de nombreuses protéines. Deux laboratoires du Centre de ...
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity
Publié le 14/05/2022
... Detry, S., Andries, J., Bloch, Y., Gabay, C., Clancy, D.M., Savvides, S.N. "Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity" Journal of Biological Chemistry., 298(5): art.n° ...
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Publié le 12/05/2022
... Ciolek, J., Zoukimian, C., Dhot, J., Burban, M., Triquigneaux, M., Lauzier, B., Guimbert, C., Boturyn, D., Ferron, M., Ciccone, L., Tepshi, L., Stura, E., Legrand, P., Robin, P., Mourier, G., Schaack, B., Fellah, I., Blanchet, G., Gauthier-Erfanian, C., ...
Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization
Publié le 11/05/2022
... Ciccone, L., Tonali, N., Fruchart-Gaillard, C., Barlettani, L., Rossello, A., Braca, A., Orlandini, E., Nencetti, S. "Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization" Crystals., 12(5): art.n° 638. (2022). ...
New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens
Publié le 10/05/2022
... Steunou, A.S., Vigouroux, A., Aumont-Nicaise, M., Plancqueel, S., Boussac, A., Ouchane, S., Moréra, S. "New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens" FEBS Journal., 289(20): 6286-6307. (2022). ...
Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate
Publié le 10/05/2022
... Royappa, A.T., Papoular, R.J., Gembicky, M., Shepard, W., Ross, A.D., Stemen, A.G., Bobbitt, J.J., Doan, D.T., Lapidus, S.H., Johnston, D.H., Filatov, A. "Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate" ...
L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Publié le 10/05/2022
... Amara, P., Saragaglia, C., Mouesca, J.M., Martin, L., Nicolet, Y. "L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases" Nature Communications., 13: art.n° 2284. (2022). ...