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Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: from a Michaelis-like complex to ThDP adducts
Publié le 05/09/2019
... Wagner, T., Boyko, A., Alzari, P.M., Bunik, V.I., Bellinzoni, M. "Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: from a Michaelis-like complex to ThDP ...
The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis
Publié le 05/09/2019
... Van Nerom, K., Tamman, H., Takada, H., Hauryliuk, V., Garcia-Pino, A. "The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis" Acta Crystallographica F., 75(8): 561-569. (2019). ...
Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues fludarabine and vidarabine
Publié le 05/09/2019
... Holzer, S., Rzechorzek, N.J., Short, I.R., Jenkyn-Bedford, M., Pellegrini, L., Kilkenny, M.L. "Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues fludarabine and vidarabine" ACS Chemical Biology., 14(9): 1904-1912. ...
Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors
Publié le 05/09/2019
... Collie, G.W., Koh, C.M., O’Neill, D.J., Stubbs, C.J., Khurana, P., Eddershaw, A., Snijder, A., Mauritzson, F., Barlind, L., Dale, I.L., Shaw, J., Phillips, C., Hennessy, E.J., Cheung, T., Narvaez, A.J. "Structural and Molecular Insight into Resistance ...
Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome
Publié le 05/09/2019
... Arrondel, C., Missoury, S., Snoek, R., Patat, J., Menara, G., Collinet, B., Liger, D., Durand, D., Gribouval, O., Boyer, O., Buscara, L., Martin, G., Machuca, E., Nevo, F., Lescop, E., Braun, D.A., Boschat, A.C., Sanquer, S., Guerrera, I.C., Revy, P., ...
Des traces d’activités biologiques disparues, découvertes dans des roches datant de 2,1 milliards d'années
Publié le 29/08/2019
... Des chercheurs de l’Université de Poitiers-CNRS, en collaboration avec la ligne de lumière Nanoscopium et une équipe internationale et pluridisciplinaire, proposent une nouvelle démarche scientifique qui pourrait permettre de révéler, dans ...
La fluorescence des rayons X, un nouvel outil pour diagnostiquer la maladie de Wilson
Publié le 30/07/2019
... Kascakova, S., Kewish, C.M., Guettier, C., Le Naour, F. "La fluorescence des rayons X, un nouvel outil pour diagnostiquer la maladie de Wilson" Hépato-Gastro & Oncologie Digestive., 24(5): 551-552. (2017). ...
Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism
Publié le 25/07/2019
... Robert-Paganin, J., Robblee, J.P., Auguin, D., Blake, T.C.A.
Bookwalter, C.S., Krementsova, E.B., Moussaoui, D., Previs, M.J., Jousset, G., Baum, J., Trybus, K.M., Houdusse, A. "Plasmodium myosin A drives parasite invasion by an atypical force generating ...
The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112
Publié le 23/07/2019
... Tran, N.V., Ernst, F.G.M., Hawley, B.R., Zorbas, C., Ulryck, N., Hackert, P., Bohnsack, K.E., Bohnsack, M.T., Jaffrey, S.R., Graille, M., Lafontaine, D.L.J. "The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112" Nucleic Acids Research. ...
A unique ferrous iron binding mode is associated to large conformational changes for the transport protein FpvC of Pseudomonas aeruginosa
Publié le 20/07/2019
... Vigouroux, A., Aumont-Nicaise, M., Boussac, A., Marty, L., Lo Bello, L., Legrand, P., Brillet, K., Schalk, I.J., Moréra, S. "A unique ferrous iron binding mode is associated to large conformational changes for the transport protein FpvC of Pseudomonas ...