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MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Publié le 12/05/2022
... Ciolek, J., Zoukimian, C., Dhot, J., Burban, M., Triquigneaux, M., Lauzier, B., Guimbert, C., Boturyn, D., Ferron, M., Ciccone, L., Tepshi, L., Stura, E., Legrand, P., Robin, P., Mourier, G., Schaack, B., Fellah, I., Blanchet, G., Gauthier-Erfanian, C., ...
Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization
Publié le 11/05/2022
... Ciccone, L., Tonali, N., Fruchart-Gaillard, C., Barlettani, L., Rossello, A., Braca, A., Orlandini, E., Nencetti, S. "Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization" Crystals., 12(5): art.n° 638. (2022). ...
New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens
Publié le 10/05/2022
... Steunou, A.S., Vigouroux, A., Aumont-Nicaise, M., Plancqueel, S., Boussac, A., Ouchane, S., Moréra, S. "New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens" FEBS Journal., 289(20): 6286-6307. (2022). ...
Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate
Publié le 10/05/2022
... Royappa, A.T., Papoular, R.J., Gembicky, M., Shepard, W., Ross, A.D., Stemen, A.G., Bobbitt, J.J., Doan, D.T., Lapidus, S.H., Johnston, D.H., Filatov, A. "Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate" ...
L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Publié le 10/05/2022
... Amara, P., Saragaglia, C., Mouesca, J.M., Martin, L., Nicolet, Y. "L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases" Nature Communications., 13: art.n° 2284. (2022). ...
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach
Publié le 30/04/2022
... Iannelli, G., Milite, C., Marechal, N., Cura, V., Bonnefond, L., Troffer-Charlier, N., Feoli, A., Rescigno, D., Wang, Y., Cipriano, A., Viviano, M., Bedford, M.T., Cavarelli, J., Castellano, S., Sbardella, G. "Turning Nonselective Inhibitors of Type I ...
L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Publié le 30/04/2022
... Amara, P., Saragaglia, C., Mouesca, J.M., Martin, L., Nicolet, Y. "L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases" Nature Communications., 13: art.n° 2284. (2022). ...
Virus hémorragique de Crimée-Congo – Résultats de biologie structurale pour de futurs vaccins et traitements
Publié le 29/04/2022
... La fièvre hémorragique de Crimée-Congo (FHCC) tient son nom d’une première description de cette maladie en Crimée en 1944, chez des militaires soviétiques, puis au Congo en 1956. Transmise à l’Homme par piqûre de tique ou contact direct avec ...
Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain
Publié le 29/04/2022
... Sigüeiro, R., Bianchetti, L., Peluso-Iltis, C., Chalhoub, S., Dejaegere, A., Osz, J., Rochel, N. "Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain" Journal of Medicinal Chemistry., 65(7) ...
The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor
Publié le 15/04/2022
... Fernández, F.J., Santos-López, J., Martínez-Barricarte, R., Querol-García, J., Martín-Merinero, H., Navas-Yuste, S., Savko, M., Shepard, W.E., Rodríguez de Córdoba, S., Vega, M.C. "The crystal structure of iC3b-CR3 αI reveals a modular recognition of the ...