RECHERCHER
Résultats de la recherche ""
The Asgard archaeal origins of Arf family GTPases involved in eukaryotic organelle dynamics
Publié le 24/01/2025
... Vargová, R., Chevreau, R., Alves, M., Courbin, C., Terry, K., Legrand, P., Eliáš,M., Ménétrey, J., Dacks, J.B., Jackson, C.L. "The Asgard archaeal origins of Arf family GTPases involved in eukaryotic organelle dynamics" Nature Microbiology., 10(2): 495 ...
Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential
Publié le 17/01/2025
... Wei, K., Arlotto, M., Overhulse, J.M., Dinh, T.A., Zhou, Y., Dupper, N.J., Yang, J., Kashemirov, B.A., Dawi, H., Garnaud, C., Bourgine, G., Mietton, F., Champleboux, M., Larabi, A., Hayat, Y., Indorato, R.L., Noirclerc-Savoye, M., Skoufias, D., Cornet, M. ...
Structural characterization of the ACDC domain from ApiAP2 proteins, a potential molecular target against apicomplexan parasites
Publié le 15/01/2025
... Le Berre, M., Tubiana, T., Reuterswärd Waldner, P., Lazar, N., Li de la Sierra-Gallay, I., Santos, J.M., Llinás, M., Nessler, S. "Structural characterization of the ACDC domain from ApiAP2 proteins, a potential molecular target against apicomplexan ...
Dynamic transitions of initiator binding coordinate the replication of the two chromosomes in Vibrio cholerae
Publié le 09/01/2025
... Niault, T., Talavera, A., Le Cam, E., Baconnais, S., Skovgaard, O., Fournes, F., Wagner, L., Tamman, H., Thompson, A., Echemendia-Blanco, D., Guzzi, N., Garcia-Pino, A., Mazel, D., Val, M.E. "Dynamic transitions of initiator binding coordinate the ...
Novel antimalarial 3-substituted quinolones isosteres with improved pharmacokinetic properties
Publié le 09/01/2025
... Ge, S., Jian, R., Xuan, Q., Zhu, Y., Ren, X., Li, W., Chen, X., Huang, R.K., Lee, C.S., Leung, S.C., Basilico, N., Parapini, S., Taramelli, D., Pinthong, N., Antonyuk, S.V., O'Neill, P.M., Sheng, Z., Hong, W.D. "Novel antimalarial 3-substituted quinolones ...
Molecular properties of the RmlT wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes
Publié le 07/01/2025
... Monteiro, R., Cereija, T.B., Pombinho, R., Voskuilen, T., Codée, J.D.C., Sousa, S., Morais-Cabral, J.H., Cabanes, D. "Molecular properties of the RmlT wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes" Nature ...
Communication between DNA polymerases and Replication Protein A within the archaeal replisome
Publié le 07/01/2025
... Martínez-Carranza, M., Vialle, L., Madru, C., Cordier, F., Tekpinar, A.D., Haouz, A., Legrand, P., Le Meur, R.A., England, P., Dulermo, R., Guijarro, J.I., Henneke, G., Sauguet, L. "Communication between DNA polymerases and Replication Protein A within ...
Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology
Publié le 11/12/2024
... Sogues, A., Leigh, K., Halingstad, E.V., Van der Verren, S.E., Cecil, A.J., Fioravanti, A., Pak, A.J., Kudryashev, M., Remaut, H. "Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology" PNAS., 121(51): art.n° ...
Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties
Publié le 04/12/2024
... Redeghieri, P., Moray, J., Kerff, F., Gohy S., Leal, T., Muyldermans, S., Vanbever, R., Morales-Yánez, F.J., Dumoulin, M. "Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting ...
Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies
Publié le 28/11/2024
... Cecil, A.J., Sogues, A., Gurumurthi, M., Lane, K.S., Remaut, H., Pak, A.J. "Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies" PNAS Nexus., 3(12): art.n° pgae538. (2024). ...