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Spéciation expérimentale du plutonium dans l’eau de mer
Publié le 18/10/2018
... La détermination des formes prédominantes des radionucléides en milieu marin constitue un axe de recherche majeur pour de nombreux instituts de recherche spécialisés dans l’impact environnemental des activités nucléaires militaire et civile. ...
Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate Reductoisomerase with β‐Arylpropyl Analogues of Fosmidomycin
Publié le 17/10/2018
... Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, D., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L. "Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate ...
Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors
Publié le 17/10/2018
... Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465 ...
Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH
Publié le 17/10/2018
... Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018). ...
Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
Publié le 17/10/2018
... El Ghachi, M., Howe, N., Huang, C.Y., Olieric, V., Warshamanage, R., Touzé, T., Weichert, D., Stansfeld, P.J., Wang, M., Kerff, F., Caffrey, M. "Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis" Nature ...
Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis
Publié le 17/10/2018
... El Ghachi, M., Howe, N., Auger, R., Lambion, A., Guiseppi, A., Delbrassine, F., Manat, G., Roure, S., Peslier, S., Sauvage, E., Vogeley, L., Rengifo-Gonzalez, J.C., Charlier, P., Mengin-Lecreulx, D. "Crystal structure and biochemical characterization of ...
Molecular Mechanisms of Drug Action: X-ray Crystallography at the Basis of Structure-based and Ligand-based Drug Design
Publié le 17/10/2018
... de Ruyck, J., Roos, G., Krammer, E.M., Prévost, M., Lensink, M.F., Bouckaert, J. "Molecular Mechanisms of Drug Action: X-ray Crystallography at the Basis of Structure-based and Ligand-based Drug Design" In Biophysical Techniques in Drug Discovery: 67-86: ...
Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Publié le 17/10/2018
... Chofor, R., Sooriyaarachchi, S., Risseeuw, M.D., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C.S., Maes, L., Coenye, T., Alex, A., Couch, R.D., Jones, T.A., Wouters, J., Mowbray, S.L., Van Calenbergh, S. "Synthesis and ...
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1
Publié le 17/10/2018
... Bloch, Y., Bouchareychas, L., Merceron, R., Składanowska,K., Van den Bossche,L., Detry,S., Govindarajan,S., Elewaut,D., Haerynck,F., Dullaers,M., Adamopoulos,I.E., Savvides, S.N. "Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate ...
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining
Publié le 09/10/2018
... Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, ...