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Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands
Publié le 11/03/2025
... Sieskind, R., Missoury, S., Madru, C., Commenge, I., Niogret, G., Hollenstein, M., Rondelez, Y., Sauguet, L., Haouz, A., Legrand, P., Delarue, M. "Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two ...
Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans DsijT
Publié le 11/03/2025
... Chevenier, A., Fanuel, M., Sokolova, E., Latorre, D.M., Jouanneau, D., Jeudy, A., Préchoux, A., Zühlke, M.K., Bartel, J., Becher, D., Czjzek, M., Ropartz, D., Michel, G., Ficko-Blean, E. "Structure, function and catalytic mechanism of the carrageenan ...
Coordination of aluminum in saponite-like material as a function of synthesis pH
Publié le 04/03/2025
... Dzene, L., Dutournié, P., Rigolet, S., Vidal, L., Lassalle-Kaiser, B., Vantelon, D., Paineau, E. "Coordination of aluminum in saponite-like material as a function of synthesis pH". Clays and Clay Minerals., 73: art.n° e8. (2025). ...
Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity
Publié le 28/02/2025
... Neuville, M., Bourgeais, M., Buratto, J., Saragaglia, C., Li, B., Galeano-Otero, I., Mauran, L., Varajao, L., Goudreau, S.R., Kauffmann, B., Thinon, E., Pasco, M., Khatib, A.M., Guichard, G. "Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C ...
Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State
Publié le 25/02/2025
... Pecqueur, L., Lombard, M., Hamdane, D. "Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State" Biomolecules., 15(3): art.n° 318. (2025). ...
Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis
Publié le 22/02/2025
... Schulze, M.S.E.D., Scholz, D., Jnoff, E., Hall, A., Melin, J., Sands, Z.A., Rodriguez, E., Andre, V.M. "Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis" ChemMedChem., 19(7): art.n° e202300548. (2024). ...
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors
Publié le 22/02/2025
... Mfuh, A.M., Boerth, J.A., Bommakanti, G., Chan, C., Chinn, A.J., Code, E., Fricke, P.J., Giblin, K.A., Gohlke, A., Hansel, C., Hariparsad, N., Hughes, S.J., Jin, M., Kantae, V., Kavanagh, S.L., Lamb, M.L., Lane, J., Moore, R., Puri, T., Quinn, T.R., Reddy ...
Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Publié le 22/02/2025
... Cellupica, E., Gaiassi, A., Rocchio, I., Rovelli, G., Pomarico, R., Sandrone, G., Caprini, G., Cordella, P., Cukier, C., Fossati, G., Marchini, M., Bebel, A., Airoldi, C., Palmioli, A., Stevenazzi, A., Steinkuhler, C., Vergani, B. "Mechanistic and ...