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Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a seven-bladed beta-propeller protein
Publié le 29/05/2025
... Yu, J., Knoppová, J., Michoux, F., Bialek, W., Cota, E., Shukla, M.K., Strašková, A., Aznar, G.P., Sobotka, R., Komenda, J., Murray, J.W., Nixon, P.J. "Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a seven-bladed beta ...
Probing Macromolecular Interactions by Loss of Solvent Content in Protein Crystals: Application to the Amyloid-β Peptide Binding to Transthyretin
Publié le 23/05/2025
... Costa-Rodrigues, D., Leite, J.P., Gales, L. "Probing Macromolecular Interactions by Loss of Solvent Content in Protein Crystals: Application to the Amyloid-β Peptide Binding to Transthyretin" Crystal Growth & Design., 25(10): 3511-3517 . (2025). ...
Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists
Publié le 23/05/2025
... Amaudrut, J., Argiriadi, M.A., Barth, M., Breinlinger, E.C., Bressac, D., Broqua, P., Calderwood, D.J., Chatar, M., Cusack, K.P., Gauld, S.B., Jacquet, S., Kamath, R.V., Kort, M.E., Lepais, V., Luccarini, J.M., Masson, P., Montalbetti, C., Mounier, L., ...
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Publié le 23/05/2025
... Tron, A.E., Belmonte, M.A., Adam, A., Aquila, B.M., Boise, L.H., Chiarparin, E., Cidado, J., Embrey, K.J., Eric Gangl, E., Gibbons, F.D., Gregory, G.P., Hargreaves, D., Hendricks, J.A., Johannes, J.W., Johnstone, R.W., Kazmirski, S.L., Kettle, J.G., Lamb, ...
Structural and physico-chemical properties of selected glasses in the (Ca1-xMgx)O-Al2O3 system
Publié le 06/05/2025
... Arkhipin, A.S., Zhomin, G.M., Kuzovchikov, S.V., Khvan, A.V., Uspenskaya, I.A. "Structural and physico-chemical properties of selected glasses in the (Ca1-xMgx)O-Al2O3 system" Chimica Techno Acta., 12(2): art.n° 12218. (2025). ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Mechanism of read-through enhancement by aminoglycosides and mefloquine
Publié le 25/04/2025
... Kolosova, O., Zgadzay, Y., Stetsenko, A., Sukhinina, A.P., Atamas, A., Validov, S., Rogachev, A., Usachev, K., Jenner, L., Dmitriev, S.E., Yusupova, G., Guskov, A., Yusupov, M. "Mechanism of read-through enhancement by aminoglycosides and mefloquine" PNAS ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity
Publié le 15/04/2025
... Cornelius, P., Mayes, B.A., Petersen, J.S., Turnquist, D.J., Dufour, P.J., Dannenberg, A.J., Shanahan, J.M., Carver, B.J. "Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and ...
How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation
Publié le 11/04/2025
... Contaldo, U., Santucci, P., Vergnes, A., Leone, P., Becam, J., Biaso, F., Ilbert, M., Ezraty, B., Lojou, E., Mazurenko, I. "How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation" JACS Au., 5(4): 1833-1844. (2025). ...