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Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function
Publié le 27/05/2025
... Dal Maso, T., Sinisgalli, C., Zilio, G., Franzin, E., Tessari, I., Pardon, E., Steyaert, J., Ballet, S., Greggio, E., Versées, W., Plotegher, N. "Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function" Nature ...
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Publié le 21/05/2025
... Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S., Versées, W. "Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity" ACS ...
Aimants torsadés : des nanomatériaux imprimés en 3D révèlent de nouveaux états magnétiques
Publié le 30/04/2025
... Des scientifiques ont utilisé l'impression 3D pour façonner des nanomatériaux imitant la structure torsadée de l'ADN, révélant ainsi de nouvelles façons de contrôler le magnétisme par la géométrie. Une équipe internationale — comprenant des ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Publié le 25/04/2025
... Seoane, S., Gogoi, P., Zárate-Ruíz, A., Peluso-Iltis, C., Peters, S., Guiberteau, T., Maestro, M.A., Pérez-Fernández, R., Rochel, N., Mouriño, A. "Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
Fractional Skyrmion Tubes in Chiral-Interfaced 3D Magnetic Nanowires
Publié le 16/04/2025
... Fullerton, J., Leo, N., Jurczyk, J., Donnelly, C., Sanz-Hernández, D., Skoric, L., Mille, N., Stanescu, S., MacLaren, D.A., Belkhou, R., Hierro-Rodriguez, A., Fernández-Pacheco, A. "Fractional Skyrmion Tubes in Chiral-Interfaced 3D Magnetic Nanowires". ...
N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle
Publié le 11/04/2025
... Ifeagwu, M.C., Guo, L., Mockler, N.M., Dong, M., Li, C., Crowley, P.B. "N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle" Crystal Growth & Design., 25(13): 4661-4665. (2025). ...
Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons.
Publié le 11/04/2025
... Ganatra, P., Wang, D.F., Ganatra, V., Dang, V.T., Nguyen, A.I. "Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons." Journal of the American Chemical Society., 146(32): 22236–22246. (2024). ...
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Publié le 10/04/2025
... Shields, J.D., Aquila, B.M., Emmons, D., Finlay, M.R.V., Gangl, E.T., Gu, C., Mlynarski, S.N., Petersen, J., Pop-Damkov, P., Li Sha, L., Simpson, I., Tavakoli, S., Tentarelli, S., Wang, H., Ye, Q., Zheng, X.L. "Design and Synthesis of Acyclic Boronic Acid ...