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Immunité - La diffraction X relève des interactions entre protéines au cœur de la défense contre les pathogènes
Publié le 17/05/2022
... En permanence, le système immunitaire identifie et détruit bactéries pathogènes, virus et autres facteurs d’infection. Le système du complément est l’un de ses composants, constitué de nombreuses protéines. Deux laboratoires du Centre de ...
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity
Publié le 14/05/2022
... Detry, S., Andries, J., Bloch, Y., Gabay, C., Clancy, D.M., Savvides, S.N. "Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity" Journal of Biological Chemistry., 298(5): art.n° ...
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Publié le 12/05/2022
... Ciolek, J., Zoukimian, C., Dhot, J., Burban, M., Triquigneaux, M., Lauzier, B., Guimbert, C., Boturyn, D., Ferron, M., Ciccone, L., Tepshi, L., Stura, E., Legrand, P., Robin, P., Mourier, G., Schaack, B., Fellah, I., Blanchet, G., Gauthier-Erfanian, C., ...
Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization
Publié le 11/05/2022
... Ciccone, L., Tonali, N., Fruchart-Gaillard, C., Barlettani, L., Rossello, A., Braca, A., Orlandini, E., Nencetti, S. "Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization" Crystals., 12(5): art.n° 638. (2022). ...
Connector theory for reusing model results to determine materials properties
Publié le 10/05/2022
... Vanzini, M., Aouina, A., Panholzer, M., Gatti, M., Reining , L. "Connector theory for reusing model results to determine materials properties" npj Computational Materials., 8: art.n° 98. (2022). ...
New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens
Publié le 10/05/2022
... Steunou, A.S., Vigouroux, A., Aumont-Nicaise, M., Plancqueel, S., Boussac, A., Ouchane, S., Moréra, S. "New insights into the mechanism of iron transport through the bacterial Ftr-system present in pathogens" FEBS Journal., 289(20): 6286-6307. (2022). ...
Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate
Publié le 10/05/2022
... Royappa, A.T., Papoular, R.J., Gembicky, M., Shepard, W., Ross, A.D., Stemen, A.G., Bobbitt, J.J., Doan, D.T., Lapidus, S.H., Johnston, D.H., Filatov, A. "Crystalline phase transitions and water-soluble complexes of copper(I) 2-hydroxyethanethiolate" ...
Delocalization of dark and bright excitons in flat-band materials and the optical properties of V2O5
Publié le 10/05/2022
... Gorelov, V., Reining, L., Feneberg, M., Goldhahn, R., Schleife, A., Lambrecht, W.R.L., Gatti, M. "Delocalization of dark and bright excitons in flat-band materials and the optical properties of V2O5" npj Computational Materials., 8: art.n° 94. (2022). ...
L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Publié le 10/05/2022
... Amara, P., Saragaglia, C., Mouesca, J.M., Martin, L., Nicolet, Y. "L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases" Nature Communications., 13: art.n° 2284. (2022). ...
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach
Publié le 30/04/2022
... Iannelli, G., Milite, C., Marechal, N., Cura, V., Bonnefond, L., Troffer-Charlier, N., Feoli, A., Rescigno, D., Wang, Y., Cipriano, A., Viviano, M., Bedford, M.T., Cavarelli, J., Castellano, S., Sbardella, G. "Turning Nonselective Inhibitors of Type I ...