RECHERCHER
Résultats de la recherche ""
Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentration and efflux activity in antibiotic intracellular accumulation
Publié le 19/10/2018
... Dumont, E., Vergalli, J., Conraux, L., Taillier, C., Vassort, A., Pajović, J., Réfrégiers, M., Mourez, M., Pagès, J.M. "Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentration and efflux ...
Qu'a apporté SOLEIL dans le domaine des diagnostics et pronostics médicaux ?
Publié le 18/10/2018
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En lien étroit avec le monde hospitalier, SOLEIL participe à l’élaboration de diagnostics précoces des maladies, et s’intéresse au développement des pathologies, avec en ligne de mire des traitements plus ...
Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate Reductoisomerase with β‐Arylpropyl Analogues of Fosmidomycin
Publié le 17/10/2018
... Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, D., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L. "Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate ...
Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors
Publié le 17/10/2018
... Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465 ...
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis
Publié le 17/10/2018
... O'Brien, D.P., Durand, D., Voegele, A., Hourdel, V., Davi, M., Chamot-Rooke, J., Vachette, P., Brier, S., Ladant, D., Chenal, A. "Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis" PloS Biology., 15(12): art.n° e2004486. ...
Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH
Publié le 17/10/2018
... Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018). ...
Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
Publié le 17/10/2018
... El Ghachi, M., Howe, N., Huang, C.Y., Olieric, V., Warshamanage, R., Touzé, T., Weichert, D., Stansfeld, P.J., Wang, M., Kerff, F., Caffrey, M. "Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis" Nature ...
Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis
Publié le 17/10/2018
... El Ghachi, M., Howe, N., Auger, R., Lambion, A., Guiseppi, A., Delbrassine, F., Manat, G., Roure, S., Peslier, S., Sauvage, E., Vogeley, L., Rengifo-Gonzalez, J.C., Charlier, P., Mengin-Lecreulx, D. "Crystal structure and biochemical characterization of ...
Molecular Mechanisms of Drug Action: X-ray Crystallography at the Basis of Structure-based and Ligand-based Drug Design
Publié le 17/10/2018
... de Ruyck, J., Roos, G., Krammer, E.M., Prévost, M., Lensink, M.F., Bouckaert, J. "Molecular Mechanisms of Drug Action: X-ray Crystallography at the Basis of Structure-based and Ligand-based Drug Design" In Biophysical Techniques in Drug Discovery: 67-86: ...
Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Publié le 17/10/2018
... Chofor, R., Sooriyaarachchi, S., Risseeuw, M.D., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C.S., Maes, L., Coenye, T., Alex, A., Couch, R.D., Jones, T.A., Wouters, J., Mowbray, S.L., Van Calenbergh, S. "Synthesis and ...