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Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors

Publié le 17/10/2018
... Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465 ...

The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain.

Publié le 17/10/2018
... Rocaboy, M., Herman, R., Sauvage, E., Remaut, H., Moonens, K., Terrak, M., Charlier, P., Kerff, F. "The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain." Molecular Microbiology., ...

First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity

Publié le 17/10/2018
... Pouyez, J., Mayard, A., Vandamme, A.M., Roussel, G., Perpète, E.A., Wouters, J., Housen, I., Michaux, C. "First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its ...

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis

Publié le 17/10/2018
... O'Brien, D.P., Durand, D., Voegele, A., Hourdel, V., Davi, M., Chamot-Rooke, J., Vachette, P., Brier, S., Ladant, D., Chenal, A. "Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis" PloS Biology., 15(12): art.n° e2004486. ...

Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH

Publié le 17/10/2018
... Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018). ...

Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum β-Lactamase CTX-M-96

Publié le 17/10/2018
... Ghiglione, B., Rodríguez, M.M., Herman, R., Curto, L., Dropa, M., Bouillenne, F., Kerff, F., Galleni, M., Charlier, P., Gutkind, G., Sauvage, E., Power, P. "Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum β ...

Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis

Publié le 17/10/2018
... El Ghachi, M., Howe, N., Huang, C.Y., Olieric, V., Warshamanage, R., Touzé, T., Weichert, D., Stansfeld, P.J., Wang, M., Kerff, F., Caffrey, M. "Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis" Nature ...

Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis

Publié le 17/10/2018
... El Ghachi, M., Howe, N., Auger, R., Lambion, A., Guiseppi, A., Delbrassine, F., Manat, G., Roure, S., Peslier, S., Sauvage, E., Vogeley, L., Rengifo-Gonzalez, J.C., Charlier, P., Mengin-Lecreulx, D. "Crystal structure and biochemical characterization of ...

Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase

Publié le 17/10/2018
... Delvaux, D., Kerff, F., Murthy, A.V.R., Lakaye, B., Czerniecki, J., Kohn, G., Wins, P., Herman, R., Gabelica, V., Heuze, F., Tordoir, X., Marée, R., Matagne, A., Charlier, P., De Pauw, E., Bettendorff, L. "Structural determinants of specificity and ...

Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase

Publié le 17/10/2018
... Delsaute, M., Berlemont, R., Dehareng, D., Van Elder, D., Galleni, M., Bauvois, C. "Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase" Acta Crystallographica F., 69(8): 828-833. (2013). ...