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Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology
Publié le 11/12/2024
... Sogues, A., Leigh, K., Halingstad, E.V., Van der Verren, S.E., Cecil, A.J., Fioravanti, A., Pak, A.J., Kudryashev, M., Remaut, H. "Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology" PNAS., 121(51): art.n° ...
Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties
Publié le 04/12/2024
... Redeghieri, P., Moray, J., Kerff, F., Gohy S., Leal, T., Muyldermans, S., Vanbever, R., Morales-Yánez, F.J., Dumoulin, M. "Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting ...
Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies
Publié le 28/11/2024
... Cecil, A.J., Sogues, A., Gurumurthi, M., Lane, K.S., Remaut, H., Pak, A.J. "Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies" PNAS Nexus., 3(12): art.n° pgae538. (2024). ...
Dimerization of ADAR1 modulates site-specificity of RNA editing
Publié le 22/11/2024
... Mboukou, A., Rajendra, V., Messmer, S., Mandl, T.C., Catala, M., Tisné, C., Jantsch, M.F., Barraud, P. "Dimerization of ADAR1 modulates site-specificity of RNA editing" Nature Communications., 15: art.n° 10051. (2024). ...
Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands
Publié le 05/11/2024
... Antonini, G., Bernardi, A., Gillon, E., Dal Corso, A., Civera, M., Belvisi, L., Varrot, A., Mazzotta, S. "Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands" Journal of Medicinal Chemistry., 67(21): 19546-19560. (2024). ...
The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization
Publié le 31/10/2024
... Ammar Khodja, L., Campanacci, V., Lippens, G., Gigant, B. "The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization" PNAS Nexus., 3(11): art.n° 487. (2024). ...
Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge
Publié le 31/10/2024
... Aimeur, S., Fas, B.A., Serfaty, X., Santuz, H., Sacquin-Mora, S., Bizouarn, T., Taly, A., Baciou, L. "Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge" Journal of Biological ...
RNase W, a conserved ribonuclease family with a novel active site
Publié le 29/10/2024
... Vayssières, M., Jüttner, M., Haas, K., Ancelin, A., Marchfelder, A., Leulliot, N., Ferreira-Cerca, S., Blaud, M. "RNase W, a conserved ribonuclease family with a novel active site" Nucleic Acids Research., 52(21): 13386–13401. (2024). ...
Ethane-oxidising archaea couple CO2 generation to F420 reduction
Publié le 23/10/2024
... Lemaire, O.N., Wegener, G., Wagner, T. "Ethane-oxidising archaea couple CO2 generation to F420 reduction" Nature Communications., 15: art.n° 9065. (2024). ...
4′-Ethynyl-2′-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
Publié le 17/10/2024
... Calbert, M.L., Chandramouly, G., Adams, C.M., Saez-Ayala, M., Kent, T., Tyagi, M., Abhinav Ayyadevara, V.S.S., Wang, Y., Krais, J.J., Gordon, J., Atkins, J., Toma, M.M., Betzi, S., Boghossian, A.S., Rees, M.G., Ronan, M.M., Roth, J.A., Goldman, A.R., ...