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Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding Protein
Publié le 17/10/2018
... Zervosen, A., Herman, R., Kerff, F., Herman, A., Bouillez, A., Prati, F., Pratt, R.F., Frère, J.M., Joris, B., Luxen, A., Charlier, P., Sauvage, E. "Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding ...
Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Publié le 17/10/2018
... Woon, E.C.Y., Zervosen, A., Sauvage, E., Simmons, K.J., Živec, M., Inglis, S.R., Fishwick, C.W.G., Gobec, S., Charlier, P., Luxen, A., Schofield, C.J. "Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors" ACS ...
Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.
Publié le 17/10/2018
... Wohlkönig, A., Remaut, H., Moune, M., Tanina, A., Meyer, F., Desroses, M., Steyaert, J., Willand, N., Baulard, A.R., Wintjens, R. "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2 ...
Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate Reductoisomerase with β‐Arylpropyl Analogues of Fosmidomycin
Publié le 17/10/2018
... Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, D., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L. "Targeting an Aromatic Hotspot in Plasmodium falciparum 1‐Deoxy‐d‐xylulose‐5‐phosphate ...
Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors
Publié le 17/10/2018
... Rondelet, G., Fleury, L., Faux, C., Masson, V., Dubois, J., Arimondo, P.B., Willems, L., Wouters, J. "Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors" Future Medicinal Chemistry., 9(13): 1465 ...
The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain.
Publié le 17/10/2018
... Rocaboy, M., Herman, R., Sauvage, E., Remaut, H., Moonens, K., Terrak, M., Charlier, P., Kerff, F. "The Crystal Structure of the Cell Division Amidase Amic Reveals the Fold of the Amin Domain, a New Peptidoglycan Binding Domain." Molecular Microbiology., ...
First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity
Publié le 17/10/2018
... Pouyez, J., Mayard, A., Vandamme, A.M., Roussel, G., Perpète, E.A., Wouters, J., Housen, I., Michaux, C. "First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its ...
Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH
Publié le 17/10/2018
... Krammer, E.M., de Ruyck, J., Roos, G., Bouckaert, J., Lensink, M.F. "Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH" Molecules., 23(7): art.n° 1641. (2018). ...
Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum β-Lactamase CTX-M-96
Publié le 17/10/2018
... Ghiglione, B., Rodríguez, M.M., Herman, R., Curto, L., Dropa, M., Bouillenne, F., Kerff, F., Galleni, M., Charlier, P., Gutkind, G., Sauvage, E., Power, P. "Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum β ...
Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
Publié le 17/10/2018
... El Ghachi, M., Howe, N., Huang, C.Y., Olieric, V., Warshamanage, R., Touzé, T., Weichert, D., Stansfeld, P.J., Wang, M., Kerff, F., Caffrey, M. "Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis" Nature ...