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Mechanism of read-through enhancement by aminoglycosides and mefloquine
Publié le 25/04/2025
... Kolosova, O., Zgadzay, Y., Stetsenko, A., Sukhinina, A.P., Atamas, A., Validov, S., Rogachev, A., Usachev, K., Jenner, L., Dmitriev, S.E., Yusupova, G., Guskov, A., Yusupov, M. "Mechanism of read-through enhancement by aminoglycosides and mefloquine" PNAS ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and Anti-metastatic Activity
Publié le 15/04/2025
... Cornelius, P., Mayes, B.A., Petersen, J.S., Turnquist, D.J., Dufour, P.J., Dannenberg, A.J., Shanahan, J.M., Carver, B.J. "Pharmacological Characterization of SDX-7320/Evexomostat: A Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-tumor and ...
How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation
Publié le 11/04/2025
... Contaldo, U., Santucci, P., Vergnes, A., Leone, P., Becam, J., Biaso, F., Ilbert, M., Ezraty, B., Lojou, E., Mazurenko, I. "How the Larger Methionine-Rich Domain of CueO from Hafnia alvei Enhances Cuprous Oxidation" JACS Au., 5(4): 1833-1844. (2025). ...
Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease
Publié le 10/04/2025
... Panek, D., Pasieka, A., Jończyk,J., Gawlińska,M., Zaręba,P., Siwek,A., Wolak,M., Mordyl,B., Głuch-Lutwin,M., Latacz,G., Brazzolotto,X., Chantegreil,F., Nachon,F., Karasova, J.Z., Pejchal, J., Mzik, M., Sestak, V., Prchal, L., Odvarkova, J., Soukup, O., ...
Que peut apporter SOLEIL à la communauté scientifique des biologistes - Rencontres scientifiques à Montpellier les 28 et 29 avril 2025
Publié le 09/04/2025
... Au programme de ces rencontres : des présentations croisées de scientifiques de Montpellier et des lignes de lumière de SOLEIL, organisées autour de deux thèmes principaux : l'imagerie et la biologie structurale. ...
Inhibition of tau neuronal internalization using anti-tau single domain antibodies
Publié le 03/04/2025
... Danis, C., Dupré, E., Bouillet, T., Denéchaud, M., Lefebvre, C., Nguyen, M., Mortelecque, J., Cantrelle, F.X., Rain, J.C., Hanoulle, X., Colin, M., Buée, L., Landrieu, I. "Inhibition of tau neuronal internalization using anti-tau single domain antibodies" ...
Molecular basis for the calcium-dependent activation of the ribonuclease EndoU
Publié le 03/04/2025
... Malard, F., Dias, K., Baudy, M., Thore, S., Vialet, B., Barthélémy, B., Fribourg, S., Karginov, F.V., Campagne, S. "Molecular basis for the calcium-dependent activation of the ribonuclease EndoU" Nature Communications., 16: art.n° 3110. (2025). ...
β-Carotene alleviates substrate inhibition caused by asymmetric cooperativity
Publié le 01/04/2025
... Liao, J., Hameed, U.F.S., Hoffmann, T.D., Kurze, E., Sun, G., Steinchen, W., Nicoli, A., Di Pizio, A., Kuttler, C., Song, C., Catici, D.A.M., Assaad-Gerbert, F., Hoffmann, T., Arold, S.T., Schwab, W.G. "β-Carotene alleviates substrate inhibition caused by ...
Phenylacetic acid metabolism in land plants: novel pathways and metabolites
Publié le 27/03/2025
... Hladík, P., Brunoni, F., Žukauskaitė,A., Zatloukal,M., Bělíček,J., Kopečný, D., Briozzo, P., Ferchaud, N., Novák, O., Pěnčík, A. "Phenylacetic acid metabolism in land plants: novel pathways and metabolites" Journal of Experimental Botany., 76(12): 3427 ...