RECHERCHER
Résultats de la recherche ""
Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis
Publié le 22/02/2025
... Schulze, M.S.E.D., Scholz, D., Jnoff, E., Hall, A., Melin, J., Sands, Z.A., Rodriguez, E., Andre, V.M. "Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis" ChemMedChem., 19(7): art.n° e202300548. (2024). ...
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors
Publié le 22/02/2025
... Mfuh, A.M., Boerth, J.A., Bommakanti, G., Chan, C., Chinn, A.J., Code, E., Fricke, P.J., Giblin, K.A., Gohlke, A., Hansel, C., Hariparsad, N., Hughes, S.J., Jin, M., Kantae, V., Kavanagh, S.L., Lamb, M.L., Lane, J., Moore, R., Puri, T., Quinn, T.R., Reddy ...
Mechanistic and Structural Insights on Difluoromethyl-1,3,4-oxadiazole Inhibitors of HDAC6.
Publié le 22/02/2025
... Cellupica, E., Gaiassi, A., Rocchio, I., Rovelli, G., Pomarico, R., Sandrone, G., Caprini, G., Cordella, P., Cukier, C., Fossati, G., Marchini, M., Bebel, A., Airoldi, C., Palmioli, A., Stevenazzi, A., Steinkuhler, C., Vergani, B. "Mechanistic and ...
Conformational fluxionality of long-chain alkene clusters in the gas phase evidenced from a combined experimental and theoretical approach
Publié le 20/02/2025
... Smith Lewin, C., Herbinet, O., Arnoux, P., Battin-Leclerc, F., Garcia, G.A., Nahon, L., Tran, L.S., Vanhove, G., Mogren Al Mogren, M., Hochlaf, M., Calvo, F., Bourgalais, J. "Conformational fluxionality of long-chain alkene clusters in the gas phase ...
The Experimental Rate Constant of the S+(2D) + H2 Reaction
Publié le 17/02/2025
... Zanchet, A., Chen-Qiu, J.L., Larregaray, P., Bonnet, L., Romanzin, C., Solem, N., Thissen, R., Alcaraz, C. "The Experimental Rate Constant of the S+(2D) + H2 Reaction" ACS Earth and Space Chemistry., 9(3): 738–745. (2025). ...
Structural insights into tecovirimat antiviral activity and poxvirus resistance
Publié le 14/02/2025
... Vernuccio, R., Martínez León, A., Poojari, C.S., Buchrieser, J., Selverian, C.N., Jaleta, Y., Meola, A., Guivel-Benhassine, F., Porrot, F., Haouz, A., Chevreuil, M., Raynal, B., Mercer, J., Simon-Loriere, S., Chandran, K., Schwartz, O., Hub, J.S., ...
Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair
Publié le 11/02/2025
... Claustre, A., Malige, M., Macheton, M., Combaret, L., Lefai, E., Fafournoux, P., Taillandier, D., Henri, J., Polge, C. "Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair" ...
RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases
Publié le 07/02/2025
... Coste, F., Mishra, A., Chapuis, C., Mance, L., Pukało,Z., Bigot,N., Goffinont, S., Gaudon, V., Garnier, N., Talhaoui, I., Castaing, B., Huet, S., Suskiewicz, M.J. "RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases" FEBS ...