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Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne
Publié le 14/04/2018
... Fournier, J.F., Clary, L., Chambon, S., Dumais, L., Harris, C.S., Millois-Barbuis, C., Pierre, R., Talano, S., Thoreau, E., Aubert, J., Aurelly, M., Bouix-Peter, C., Brethon, A., Chantalat, L., Christin, O., Comino, C., El-Bazbouz, G., Ghilini, A.L., ...
Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
Publié le 11/04/2018
... Hu, H., Nemecz, A., Van Renterghem, C., Fourati, Z., Sauguet, L., Corringer, P.J., Delarue, M. "Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation" PNAS., 115(17): E3959-E3968. ...
Lytic xylan oxidases from wood-decay fungi unlock biomass degradation
Publié le 10/04/2018
... Couturier, M., Ladevèze, S., Sulzenbacher, G., Ciano, L., Fanuel, M., Moreau, C., Villares, A., Cathala, B., Chaspoul, F., Frandsen, K.E., Labourel, A., Herpoël-Gimbert, I., Grisel, S., Haon, M., Lenfant, N., Rogniaux, H., Ropartz, D., Davies, G.J., Rosso ...
The plant defense signal galactinol is specifically used as a nutrient by the bacterial pathogen Agrobacterium fabrum
Publié le 04/04/2018
... Meyer, T., Vigouroux, A., Aumont-Nicaise, M., Comte, G., Vial, L., Lavire, C., Morera, S. "The plant defense signal galactinol is specifically used as a nutrient by the bacterial pathogen Agrobacterium fabrum" Journal of Biological Chemistry., 293(21): ...
The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design
Publié le 27/03/2018
... Ronin, C., Mendes Costa, D., Tavares, J., Faria, J., Ciesielski, F., Ciapetti, P., Smith, T.K., MacDougall, J., Cordeiroda-Silva, A., Pemberton, I.K. "The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: ...
Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs
Publié le 20/03/2018
... Alam, T., Alazmi, M., Naser, R., Huser, F., Momin, A.A., Walkiewicz, K.W., Canlas, C.G., Huser, R.G., Ali, A., Merzaban, J., Bajic, V.B., Gao, X., Arold, S.T. "Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) ...
Structural study of the C-terminal domain of non-structural protein 1 from Japanese encephalitis virus
Publié le 16/03/2018
... Poonsiri, T., Wright, G.S.A., Diamond, M.S., Turtle, L., Solomon, T., Antonyuk, S.V. "Structural study of the C-terminal domain of non-structural protein 1 from Japanese encephalitis virus" Journal of Virology., 92(7): art.n° e01868-17. (2018). ...
Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
Publié le 14/03/2018
... Nikolic, J., Belot, L., Raux, R., Legrand, P., Gaudin, Y., Albertini, A.A. "Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein" Nature Communications., 9: art.n° 1029. (2018). ...
Structure Guided Lead Generation towards non-chiral M. tuberculosis Thymidylate Kinase Inhibitors
Publié le 08/03/2018
... Song, L., Merceron, R., Gracia, B., Quintana, A.L., Risseeuw, M.D.P., Hulpia, F., Cos, P., Ainsa, J.A., Munier-Lehmann, H., Savvides, S.N., Van Calenbergh, S. "Structure Guided Lead Generation towards non-chiral M. tuberculosis Thymidylate Kinase ...
The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth
Publié le 08/03/2018
... Pellegrino, S.
Meyer, M., Zorbas, C., Bouchta, S.A., Saraf, K., Pelly, S.C., Yusupova, G., Evidente, A., Mathieu, V., Kornienko, A., Lafontaine, D.L.J., Yusupov, M. "The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer ...