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An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics
Publié le 05/06/2018
... Blanc, F., Isabet, T., Benisty, H., Sweeney, H.L., Cecchini, M., Houdusse, A. "An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics" PNAS., 115(24): 6213-6218. (2018). ...
Effect of non-canonical amino acids on protein-carbohydrate interactions: Structure, dynamics and carbohydrate affinity of a lectin engineered with fluorinated tryptophan analogs.
Publié le 31/05/2018
... Tobola, F., Lelimousin, M., Varrot, A., Gillon, E., Darnhofer, B., Blixt, O., Birner-Gruenberger, R., Imberty, A., Wiltschi, B. "Effect of non-canonical amino acids on protein-carbohydrate interactions: Structure, dynamics and carbohydrate affinity of a ...
Synthesis, crystallization studies and in vitro characterization of novel cinnamic acid derivatives as SmHDAC8 inhibitors for the treatment of Schistosomiasis
Publié le 29/05/2018
... Bayer, T., Chakrabarti, A., Lancelot, J., Shaik, T.B., Hausmann, K., Melesina, J., Schmidtkunz, K., Marek, M., Erdmann, F., Schmidt, M., Robaa, D., Romier, C., Pierce, R.J., Jung, M., Sippl, W. "Synthesis, crystallization studies and in vitro ...
Cell adhesion promoted by a unique Shigella IpaA vinculin- and talin-binding site
Publié le 25/05/2018
... Valencia-Gallardo, C.M., Bou-Nader, C., Aguilar, D., Carayol, N., Quenech'Du, N., Pecqueur, L., Park, H., Fontecave, M., Izard, T., Tran Van Nhieu, G. "Cell adhesion promoted by a unique Shigella IpaA vinculin- and talin-binding site". BioRxiv., preprint: ...
Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family
Publié le 25/05/2018
... Klychnikov, O., Shamorkina, T.M., Weeks, S.D., van Leeuwen, H.C., Corver, J., Drijfhout, J.W., van Veelen, P.A., Sluchanko, N.N., Strelkov, S.V., Hensbergen, P.J. "Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the ...
A metal-regulated AMPylation/deAMPylation switch in FIC proteins
Publié le 25/05/2018
... Veyron, S., Oliva, G., Rolando, M., Buchrieser, C., Peyroche, G., Cherfils, J. "A metal-regulated AMPylation/deAMPylation switch in FIC proteins". BioRxiv., preprint: (2018). ...
Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
Publié le 23/05/2018
... Das, P., Babbar, P., Malhotra, N., Sharma, M., Jachak, G.R., Gonnade, R.G., Shanmugam, D., Harlos, K., Yogavel, M., Sharma, A., Reddy, D.S. "Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite ...
Synthesis of Avibactam Derivatives and Activity on β‐Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria
Publié le 16/05/2018
... Edoo, Z., Iannazzo, L., Compain, F., Li de la Sierra-Gallay, I., van Tilbeurgh, H., Fonvielle, M., Bouchet, F., Le Run, E., Mainardi, J.L., Arthur, M., Ethève‐Quelquejeu, M., Hugonnet, J.E. "Synthesis of Avibactam Derivatives and Activity on β‐Lactamases ...
Development of Thioaryl-based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR and Crystallographic Studies
Publié le 15/05/2018
... Nuti, E., Cuffaro, D., Bernardini, E., Camodeca, C., Panelli, L., Chaves, S., Ciccone, L., Tepshi, L., Vera, L., Orlandini, E., Nencetti, S., Stura, E.A., Santos, M.A., Dive, V., Rossello, A. "Development of Thioaryl-based Matrix Metalloproteinase-12 ...
Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists
Publié le 15/05/2018
... Gogoi, P., Seoane, S., Sigueiro, R., Guiberteau, T., Maestro, M.A., Perez-Fernandez, R., Rochel, N., Mouriño, A. "Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists" Journal of Medicinal Chemistry., 61(11): 4928–4937. ...